Corticosteroid-containing pharmaceutical composition
View Patent ↗A foamable pharmaceutical composition comprising a corticosteroid, a quick-break foaming agent, a propellant and a buffering agent, sufficient to buffer the composition to within the range of pH 3.0 to 6.0 is disclosed. The quick-break foaming agent typically comprises an aliphatic alcohol, water, a fatty alcohol and a surface active agent. Due to the nature of the compositions of the invention, they are especially well-suited for use in the treatment of various skin diseases, and in particular, in the treatment of scalp psoriasis.
1. A foamable pharmaceutical composition adapted for topical administration having the following composition:
% w/w
Betamethasone Valerate
0.120
Cetyl Alcohol BP
1.100
Octadecan-1-ol BP
0.500
Polysorbate 60 BP
0.400
Ethanol
57.790
Purified Water
33.690
Propylene Glycol BP
2.000
Citric Acid Anhydrous BP
0.073
Potassium Citrate
0.027
Butane/Propane
4.300
100.000.