IP Library › Granted Patent US 7,163,799
Granted Patent B2
US 7,163,799 · App. 10/258,423 · Granted Jan 16, 2007

Neuromedin U receptor NMUR2 and nucleotides encoding it

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Quick Facts
Patent No.
US 7,163,799
App. No.
10/258,423
Granted
Jan 16, 2007
Kind
B2
Abstract

A new neuromedin U receptor, designated NMUR2 has been found, which is involved in modulation of feeding behavior in mammals. Ligands of this receptor are able to modulate eating, and weight gain. Amino acid sequences of the human and rat forms, as well as their nucleic acid sequences are given.

Claims (3)

1. A method to identify compounds which modulate neuromedin U receptor 2 (NMUR2) activity comprising:

(a) contacting the compound and a NMUR2 receptor as set forth in SEQ ID NO:2; and

(b) determining if the activity of the NMUR2 receptor is modulated by measuring changes of intracellular calcium concentration.

Assignments (3)
CHANGE OF NAME Recorded Jan 28, 2010
From: MERCK & CO., INC.
To: MERCK SHARP & DOHME CORP.
Reel/Frame 023861/0349 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 3, 2006
From: LYNCH, KEVIN R.
To: UNIVERSITY OF VIRGINIA
Reel/Frame 017117/0066 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 3, 2006
From: UNIVERSITY OF VIRGINIA
To: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
Reel/Frame 017117/0124 →