IP Library Granted Patent US 7,336,809
Granted Patent B2
US 7,336,809 · App. 10/261,196 · Granted Feb 26, 2008

Segmentation in medical images

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Quick Facts
Patent No.
US 7,336,809
App. No.
10/261,196
Granted
Feb 26, 2008
Kind
B2
Abstract

A method and system of volume segmentation is disclosed. To address throughput speed and accuracy requirements, the segmentation is divided into two stages: presegmentation and detailed segmentation. In presegmentation, a digital image volume is processed to identify anatomical structures from image backgrounds in a gross manner possibly at reduced image resolution. Detailed segmentation then involves refining and segmenting further the fine details within the anatomical structures identified by presegmentation. One result of the overall volume segmentation algorithm is a volume in which segmented regions of interest, such as nodules, are identified.

Claims (14)

1. A method of segmenting information to identify organ nodules in a series of digital images comprising:

forming from the digital images a series of reduced resolution images having a spatial resolution that is coarser than that of said digital images;

processing the reduced resolution images to identify a reduced resolution body region and a reduced resolution background region;

using the identification of the reduced resolution body region and the reduced resolution background region to identify a body region and a background region in the digital images;

processing an organ region in the digital images to identify a boundary of an organ; and

processing the digital images to identify a region of interest in the organ.

2. The method of claim 1 wherein the organ boundary is a pleural boundary.

3. The method of claim 2 wherein the region of interest is a pleural nodule.

4. The method of claim 1 wherein processing the reduced resolution images to identify a body region and a background region comprises:

identifying in the reduced resolution images seed points at image voxels having gray level intensities exceeding a first predetermined threshold;

growing volumes from the seed points to include voxels having gray level intensities exceeding a second predetermined threshold;

identifying the body region as the largest volume grown; and

growing the background region inwards from the periphery of the reduced resolution image to the volume identified as the body region.

5. The method of claim 4 further comprising growing remaining unidentified voxels and selecting a largest or first two largest volumes as a lung field.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 5, 2012
From: MEVIS MEDICAL SOLUTIONS, INC.
To: MEVIS MEDICAL SOLUTIONS AG
Reel/Frame 028897/0942 →
LIEN RELEASE OF SPECIFIC PATENTS AT REEL/FRAME: 020024/0231 AND REEL/FRAME: 021301/0838 Recorded May 21, 2009
From: GOLDMAN SACHS CREDIT PARTNERS L.P., AS COLLATERAL AGENT
To: R2 TECHNOLOGY, INC.
Reel/Frame 022719/0910 →
PATENT SECURITY AGREEMENT Recorded Jul 29, 2008
From: R2 TECHNOLOGY, INC.
To: GOLDMAN SACHS CREDIT PARTNERS L.P., AS COLLATERAL AGENT
Reel/Frame 021301/0838 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 25, 2008
From: R2 TECHNOLOGY, INC.
To: MEVIS MEDICAL SOLUTIONS, INC.
Reel/Frame 021147/0401 →
PATENT SECURITY AGREEMENT Recorded Oct 26, 2007
From: R2 TECHNOLOGY, INC.
To: GOLDMAN SACHS CREDIT PARTNERS L.P.
Reel/Frame 020024/0231 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 29, 2003
From: ZENG, XIAOLAN; ZHANG, WEI; SCHNEIDER, ALEXANDER C.
To: R2 TECHNOLOGY, INC.
Reel/Frame 013714/0233 →