IP Library Granted Patent US 7,147,712
Granted Patent B2
US 7,147,712 · App. 10/263,366 · Granted Dec 12, 2006

Method of semiconductor nanoparticle synthesis

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Quick Facts
Patent No.
US 7,147,712
App. No.
10/263,366
Granted
Dec 12, 2006
Kind
B2
Abstract

A method is described for the manufacture of semiconductor nanoparticles. Improved yields are obtained by use of a reducing agent or oxygen reaction promoter.

Claims (51)

1. A method of producing nanoparticles comprising.

(a) mixing a first precursor and at least one coordinating solvent to form a first mixture;

(b) exposing the first mixture to a reaction promoter, different from the coordinating solvent, selected from the group consisting of oxygen and a reducing agent, to thereby reduce the first precursor's valency;

(c) heading the first mixture to a temperature that is sufficiently high to of form nanoparticles when a second precursor is added;

(d) introducing a second precursor into the first mixture after the first precursor's valency has been reduced to form a second mixture thereby resulting in the formation of a plurality of nanoparticles; and

(e) cooling the second mixture to stop further growth of the nanoparticles.

2. The method of claim 1 wherein the reaction promoter is a reducing agent.

3. The method of claim 2 wherein the exposing step comprises adding the reducing agent to the first mixture.

4. The method of claim 2 wherein the reducing agent is a chemical reducing agent selected from the group consisting of tertiary, secondary, and primary phosphines; amines; hydrazines; hydroxyphenyl compounds; hydrogen; hydrides; metals; boranes; aldehydes; alcohols; thiols; reducing halides; and polyfunctional reductants.

5. The method of claim 2 wherein the reducing agent is a cathode.

6. The method of claim 5 wherein the cathode is made of a material selected from the group consisting of platinum, silver, and carbon.

7. The method of claim 1 wherein the reaction promoter is oxygen.

8. The method of claim 7 wherein the exposing step comprises directly exposing the first mixture to a source of oxygen.

9. The method of claim 7 wherein the oxygen is formed in situ.

10. The method of claim 9 wherein the oxygen is formed by a redox reaction.

11. The method of claim 10 wherein the exposing step comprises adding a reducing agent selected from the group consisting of tertiary, secondary, and primary phosphines; amines; hydrazines; hydroxyphenyl compounds; hydrogen; hydrides; metals; boranes; aldehydes; alcohols; thiols; reducing halides; and polyfunctional reductants.

12. The method of claim 7 wherein the exposing step comprises exposing a coordinating solvent to a source of oxygen and adding the exposed coordinating solvent to the mixture.

13. The method of claim 1 wherein the coordinating solvent is selected from the group consisting of amines, alkyl phosphines, alkyl phosphine oxides, fatty acids, ethers, furans, phospho-acids, pyridines, alkenes, alkynes and combinations thereof.

14. The method of claim 13 wherein the coordinating solvent is pure.

15. The method of claim 1 wherein the mixing step further includes mixing a ligand with the first precursor and coordinating solvent.

16. The method of claim 15 wherein the ligand is selected from the group consisting of phospho-acids, carboxylic acids, amines, amides, alcohols, ethers, alkenes, and alkynes.

17. The method of claim 16 wherein the ligand is a phosphonic acid.

18. The method of claim 17 wherein the phosphonic acid is selected from the group consisting of hexylphosphonic acid and tetradecylphosphonic acid.

19. The method of claim 1 wherein the coordinating solvent is a mixture of a non-coordinating solvent and a ligand.

20. The method of claim 19 wherein the non-coordinating solvent is an alkane.

21. The method of claim 19 wherein the ligand is selected from the group consisting of phospho-acids, carboxylic acids, amines, amides, alcohols, ethers, alkenes, and alkynes.

22. The method of claim 1 wherein the nanoparticles are semiconductive.

23. The method of claim 22 wherein the first precursor is selected from the group consisting of Group 2, 12, 13 and 14 element-containing compounds.

24. The method of claim 22 wherein the second precursor is selected from the group consisting of Groups 14, 15 and 16 element-containing compounds.

25. The method of claim 1 which further comprises producing a nanoparticle shell.

26. The method of claim 25 wherein the shell producing step comprises:

(a′) mixing the nanoparticles with at least one coordinating solvent to form a third mixture;

(b′) heating the third mixture to a temperature that is sufficiently high to form a shell on the nanoparticles when third and fourth precursors are added;

(c′) introducing third and fourth precursors into the third mixture after heating the third mixture form a fourth mixture thereby resulting in the formation of shells on a plurality of nanoparticles; and

(d′) cooling the third mixture to stop further growth of the shell; wherein the method further comprises exposing the third or fourth mixture to a reaction promoter selected from the group consisting of oxygen and a reducing agent.

27. The method of claim 26 wherein an additive or additive precursor is included in step (a′).

28. A method of producing semiconductive nanoparticles having a valency “n ”, comprising:

(a) mixing a first precursor having a valency “c” and at least one coordinating solvent to form a first mixture;

(b) exposing the first mixture to a reaction promoter different from the coordinating solvent wherein the reaction promoter converts the valency of the first precursor to a valency “a”;

(c) heating the first mixture to a temperature that is sufficiently high to form nanoparticles when a second precursor is added;

(d) introducing a second precursor into the first mixture, the first mixture comprising the first precursor with the valency “a”, to form a second mixture thereby resulting in the formation of a plurality of nanoparticles; wherein the second precursor has a valency “b”, and wherein a+b=n and c+b.≠n; and

(e) cooling the second mixture to stop further growth of the nanoparticles.

29. The method of claim 28 wherein the reaction promoter is a reducing agent.

30. The method of claim 29 wherein the reaction promoter is a cathode.

31. The method of claim 30 wherein the cathode is made of a material selected from the group consisting of platinum, silver and carbon.

32. The method of claim 29 wherein the reducing agent is a chemical reducing agent selected from the group consisting of tertiary, secondary, and primary phosphines; amines; hydrazines; hydroxyphenyl compounds; hydrogen; hydrides; metals; boranes; aldehydes; alcohols; thiols; reducing halides; and polyfunctional reductants.

33. The method of claim 32 wherein the coordinating solvent is pure.

34. The method of claim 28 wherein the reaction promoter is a source of oxygen.

35. The method of claim 28 wherein the reaction promoter is oxygen that is formed in situ by a redox reaction.

36. The method of claim 35 wherein the exposing step comprises adding a reducing agent selected from the group consisting of tertiary, secondary, and primary phosphines; amines; hydrazines; hydroxyphenyl compounds; hydrogen; hydrides; metals; boranes; aldehydes; alcohols; thiols; reducing halides; and polyfunctional reductants.

37. The method of claim 28 wherein the step of heating the first mixture occurs prior to introducing the second precursor.

Assignments (4)
LIEN RELEASE Recorded Apr 9, 2013
From: BANK OF AMERICA, N.A.
To: LIFE TECHNOLOGIES CORPORATION
Reel/Frame 030182/0461 →
SECURITY AGREEMENT Recorded Dec 5, 2008
From: LIFE TECHNOLOGIES CORPORATION
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 021975/0467 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 7, 2005
From: QUANTUM DOT CORPORATION
To: INVITROGEN CORP.
Reel/Frame 016862/0372 →
SECURITY AGREEMENT Recorded Feb 16, 2005
From: QUANTUM DOT CORPORATION
To: INSTITUTIONAL VENTURE PARTNERS VII, L.P.; INSTITUTIONAL VENTURE MANAGEMENT VII, L.P.; ABINGWORTH BIOVENTURES IIA LP; SCHRODER VENTURES INTERNATIONAL LIFE SCIENCES FUND II LP1; SCHRODER VENTURES INTERNATIONAL LIFE SCIENCES FUND II LP2; SCHRODER VENTURES INTERNATIONAL LIFE SCIENCES FUND II LP3; SV NOMINEES LIMITED ON BEHALF OF SCHRODER VENTURES INVESTMENTS LIMITED; SCHRODER VENTURES INTERNATIONAL LIFE SCIENCES FUND II GROUP CO-INVESTMENT SCHEME; SCHRODER VENTURES INTERNATIONAL LIFE SCIENCES FUND II STRATEGIC PARTNERS LP; FRAZIER HEALTHCARE III, L.P.; FRAZIER AFFILIATES III, L.P.; BB BIOVENTURES L.P.; MPM ASSET MANAGEMENT INVESTORS 2000 A LLC; MPM BIOVENTURES PARALLEL FUND, L.P.
Reel/Frame 015687/0106 →