IP Library › Granted Patent US 7,049,060
Granted Patent B2
US 7,049,060 · App. 10/268,561 · Granted May 23, 2006

HCV anti-core monoclonal antibodies

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Quick Facts
Patent No.
US 7,049,060
App. No.
10/268,561
Granted
May 23, 2006
Kind
B2
Abstract

Monoclonal antibodies that specifically bind to HCV core antigen. Also provided are hybridoma cell lines which secrete these antibodies, methods for making and using these antibodies, including kits that include these antibodies.

Claims (6)

1. A hybridoma cell line corresponding to the ATCC number selected from the group consisting of PTA-3799, PTA-3800, PTA-3801, PTA-3802, PTA-3803, PTA-3804, PTA-3805, PTA-3806, PTA-3807, PTA-3808, PTA-3809, PTA-3810, PTA-3811, PTA-3812, and PTA-3813.

2. A monoclonal antibody secreted by any one of the hybridoma cell lines claimed in claim 1 .

3. Assay kits that contain one or more of the monoclonal antibodies claimed in claim 2 .

4. A method for the detection of HCV core antigens comprising:

1) contacting a sample that may contain said HCV core antigens with one or more of the monoclonal antibodies claimed in claim 2 ; and

2) detecting the presence of immune complexes as an indication of the presence of HCV core antigen.

Assignments (5)
RELEASE (REEL 060220 / FRAME 0711) Recorded Aug 22, 2025
From: BANK OF AMERICA, N.A.
To: QUIDEL CORPORATION; BIOHELIX CORPORATION; DIAGNOSTIC HYBRIDS, INC.; QUIDEL CARDIOVASCULAR INC.; ORTHO-CLINICAL DIAGNOSTICS, INC.; CRIMSON U.S. ASSETS LLC; CRIMSON INTERNATIONAL ASSETS LLC; MICRO TYPING SYSTEMS, INC.
Reel/Frame 072577/0536 →
RELEASE OF SECURITY INTEREST Recorded May 31, 2022
From: BANK OF AMERICA, N.A.
To: ORTHO-CLINICAL DIAGNOSTICS, INC.; CRIMSON U.S. ASSETS LLC; CRIMSON INTERNATIONAL ASSETS LLC
Reel/Frame 060219/0571 →
SECURITY AGREEMENT Recorded May 31, 2022
From: QUIDEL CORPORATION; BIOHELIX CORPORATION; DIAGNOSTIC HYBRIDS, INC.; QUIDEL CARDIOVASCULAR INC.; ORTHO-CLINICAL DIAGNOSTICS, INC.; CRIMSON U.S. ASSETS LLC; CRIMSON INTERNATIONAL ASSETS LLC; MICRO TYPING SYSTEMS, INC.
To: BANK OF AMERICA, N.A.
Reel/Frame 060220/0711 →
SECURITY INTEREST Recorded Jul 3, 2014
From: ORTHO-CLINICAL DIAGNOSTICS, INC; CRIMSON U.S. ASSETS LLC; CRIMSON INTERNATIONAL ASSETS LLC
To: BARCLAYS BANK PLC, AS COLLATERAL AGENT
Reel/Frame 033276/0104 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 12, 2003
From: BAHL, CHANDER
To: ORTHO-CLINICAL DIAGNOSTICS, INC.
Reel/Frame 014164/0210 →