Smooth muscle controller
View Patent ↗A method of promoting the healing of a lesion in a smooth muscle, comprising selecting a smooth muscle portion having a lesion and applying a non-excitatory electrical field to the portion, which field reduces the mechanical activity of the portion.
1. Apparatus for controlling at least the local activity of a portion of an in vivo smooth muscle in the GI tract for long term therapeutic purposes, said apparatus comprising:
a plurality of electrodes, adapted to be in contact with said portion of smooth muscle to be controlled; and
a controller which electrifies said electrodes with an electrical field, which comprises at least a non-excitatory electric field, wherein said non-excitatory electric field does not generate a propagating action potential in said smooth muscle and said non-excitatory electrical field modifies the reaction of said smooth muscle to an activation signal; and wherein said controller is programmed with parameters that are suitable to the activation profile of said smooth muscle.
2. Apparatus according to claim 1 , additionally comprising an electrical activity sensor which detects electrical activity at the portion and wherein the controller electrifies the electrodes responsive to signals from said sensor.
3. Apparatus according to claim 2 , wherein the electrification at each of the electrodes is responsive to its local electrical activity.
4. Apparatus according to claim 2 , wherein the electrical activity sensor senses electrical activity through ones of the plurality of electrodes.
5. Apparatus according to claim 1 , additionally comprising an impedance sensor, which senses at least one impedance between selected ones of the plurality of electrodes.
6. Apparatus according to claim 1 , additionally comprising a force transducer which detects mechanical activity at the portion and wherein the controller electrifies the electrodes responsive to signals from said transducer.
7. Apparatus according to claim 6 , wherein the controller applies an inhibitory electric field to the muscle, when the mechanical activity is above a certain threshold.
8. Apparatus according to claim 6 , wherein the electrification at each of said electrodes is responsive to its local mechanical activity.
9. Apparatus according to claim 1 , wherein the non-excitatory field inhibits mechanical activity at the portion.
10. Apparatus according to claim 1 , wherein the non-excitatory field reduces the force of contraction at the portion.
11. Apparatus according to claim 1 , wherein the non-excitatory field increases the force of contraction at the portion.
12. Apparatus according to claim 1 , wherein the controller electrifies at least one of the electrodes with an excitatory electric field.
13. Apparatus according to claim 1 , wherein the plurality of electrodes are arranged in a two-dimensional matrix.
14. Apparatus according to claim 1 , wherein the controller selectively electrifies ones of the plurality of electrodes to selectively generate one of two perpendicular electric fields.
15. Apparatus according to claim 1 , wherein the controller is adapted to be implanted inside a stomach and attached to the stomach wall.
16. Apparatus according to claim 1 , wherein the controller is adapted to be implanted inside the body and outside a portion of the GI tract.
17. Apparatus according to claim 1 , wherein the electrodes are adapted to be implanted inside the body while the controller is adapted to be situated outside the body.
18. Apparatus according to claim 17 , wherein the electrodes are adapted to be disconnected from the smooth muscle from outside the body.