Analgesic and anti-inflammatory compositions containing COX-2 inhibitors
View Patent ↗The present invention is directed to an analgesic composition which consists essentially of a cyclooxygenase-2 inhibitor and a compound selected from the group consisting of non-steroidal anti-inflammatory drugs, acetaminophen and mixtures thereof. The present invention further is directed to a method for inducing analgesia through the administration of such a composition to a patient.
1. A composition consisting essentially of (a) celecoxib and (b) ibuprofen.
2. The composition of claim 1 wherein celecoxib is present in amounts ranging from about 25 to about 200 mg and ibuprofen is present in amounts ranging from about 50 to about 800 mg.
3. The composition of claim 1 wherein celecoxib is present in amounts ranging from about 100 to about 200 mg and ibuprofen is present in amounts ranging from about 200 to about 400 mg.
4. The composition of claim 1 wherein celecoxib is present in an amount of about 200 mg and ibuprofen is present in an amount of about 400 mg.
5. A method of alleviating pain and/or inflammation comprising administering to a mammal exhibiting pain, an analgesia-inducing amount of a composition consisting essentially of (a) celecoxib and (b) ibuprofen.
6. The method of claim 5 wherein celecoxib is present in amounts ranging from about 25 to about 200 mg and ibuprofen is present in amounts ranging from about 50 to about 800 mg.
7. The method of claim 5 wherein celecoxib is present in amounts ranging from about 100 to about 200 mg and ibuprofen is present in amounts ranging from about 200 to about 400 mg.
8. The method of claim 5 wherein celecoxib is present in an amount of about 200 mg and ibuprofen is present in an amount of about 400 mg.
9. A method of potentiating ibuprofen thereof by administering celecoxib concurrently therewith to a mammal exhibiting pain, wherein the ibuprofen and the celecoxib are each administered in an analgesia-inducing amount.