IP Library › Granted Patent US 7,022,700
Granted Patent B2
US 7,022,700 · App. 10/309,527 · Granted Apr 4, 2006

Method of increasing neutrophil production using optically-pure (R)-2,3-benzodiazepines

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Quick Facts
Patent No.
US 7,022,700
App. No.
10/309,527
Granted
Apr 4, 2006
Kind
B2
Abstract

Compounds according to formula I: wherein R 1 , R 2 , R 3 , R 4 , R 5 and n are as defined herein, are administered to increase neutrophil levels in mammels.

Claims (1)

1. A method of increasing the absolute neutrophil count in an individual, comprising administering to said individual an effective amount of (R) -1-(3,4-dimethoxyphenyl-4-methyl-5-ethyl-7,8-dimethoxy-5H-2,3-benzodiazepine substantially free of the corresponding (S)-enantiomer, or a pharmaceutically-acceptable salt thereof.

Assignments (2)
TO ADD RECEIVING PARTY'S ADDRESS Recorded Jan 3, 2007
From: VELA PHARMACEUTICALS INC.
To: VELA ACQUISITION CORPORATION
Reel/Frame 018700/0352 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 11, 2003
From: HARRIS, HERBERT W.; KUCHARIK, ROBERT F.
To: VELA PHARMACEUTICALS, INC.
Reel/Frame 013741/0037 →