IP Library › Granted Patent US 6,986,740
Granted Patent B2
US 6,986,740 · App. 10/314,840 · Granted Jan 17, 2006

Ultrasound contrast using halogenated xanthenes

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Quick Facts
Patent No.
US 6,986,740
App. No.
10/314,840
Granted
Jan 17, 2006
Kind
B2
Abstract

New contrast agents for ultrasound imaging and methods for use of such agents for imaging of human or animal tissue are described, wherein a primary active component of such medicaments is a halogenated xanthene or halogenated xanthene derivative. Preferably, the halogenated xanthene is Rose Bengal or a functional derivative of Rose Bengal.

Claims (6)

1. A method for imaging human or animal tissue comprising the steps of:

administering an ultrasound contrast agent to a patient, a portion of said ultrasound contrast agent being retained in tissue of interest; and

imaging said tissue with ultrasound to identify said tissue,

wherein said ultrasound contrast agent is a halogenated xanthene and said ultrasound contrast agent does not include a liposome or microbubble.

2. The method of claim 1 wherein said halogenated xanthene is present in a concentration of greater than about 0.001% to less than about 20%.

3. The method of claim 1 wherein said halogenated xanthene is Rose Bengal.

Assignments (17)
CHANGE OF NAME Recorded May 24, 2018
From: PROVECTUS PHARMACEUTICALS, INC.
To: PROVECTUS BIOPHARMACEUTICALS, INC.
Reel/Frame 046239/0975 →
SECURITY INTEREST Recorded Apr 10, 2018
From: PROVECTUS BIOPHARMACEUTICALS, INC.; PROVECTUS PHARMATECH, INC.; PROVECTUS BIOTECH, INC.; PURE-IFIC, INC.
To: MILLENNIUM TRUST CO. LLC
Reel/Frame 045489/0315 →
SECURITY INTEREST Recorded Apr 10, 2018
From: PROVECTUS BIOPHARMACEUTICALS, INC.; PROVECTUS PHARMATECH, INC.; PROVECTUS BIOTECH, INC.; PURE-IFIC, INC.
To: LARCEN, MARDELL
Reel/Frame 045489/0699 →
SECURITY INTEREST Recorded Apr 10, 2018
From: PROVECTUS BIOPHARMACEUTICALS, INC.; PROVECTUS PHARMATECH, INC.; PROVECTUS BIOTECH, INC.; PURE-IFIC, INC.
To: TROUT, JONH W.; TROUT, JOSH HUDSON
Reel/Frame 045877/0656 →
SECURITY INTEREST Recorded Apr 10, 2018
From: PROVECTUS BIOPHARMACEUTICALS, INC.; PROVECTUS PHARMATECH, INC.; PROVECTUS BIOTECH, INC.; PURE-IFIC, INC.
To: WACHTER, ERIC A.
Reel/Frame 045879/0779 →
SECURITY INTEREST Recorded Apr 10, 2018
From: PROVECTUS BIOPHARMACEUTICALS, INC.; PROVECTUS PHARMATECH, INC.; PROVECTUS BIOTECH, INC.; PURE-IFIC, INC.
To: TIMOTHY WILLIAMS REVOCABLE TRUST
Reel/Frame 045489/0193 →
SECURITY INTEREST Recorded Apr 9, 2018
From: PROVECTUS BIOPHARMACEUTICALS, INC.; PROVECTUS PHARMATECH, INC.; PROVECTUS BIOTECH, INC.; PURE-IFIC, INC.
To: SCOTT, TIMOTHY C.; SCOTT, LEIGH ANNE
Reel/Frame 045478/0270 →
SECURITY INTEREST Recorded Apr 9, 2018
From: PROVECTUS BIOPHARMACEUTICALS, INC.; PROVECTUS PHARMATECH, INC.; PROVECTUS BIOTECH, INC.; PURE-IFIC, INC.
To: FORTUNATO, PAUL M.; FORTUNATO, KATHLEEN E.
Reel/Frame 045478/0511 →
SECURITY INTEREST Recorded Apr 9, 2018
From: PROVECTUS BIOPHARMACEUTICALS, INC.; PROVECTUS PHARMATECH, INC.; PROVECTUS BIOTECH, INC.; PURE-IFIC, INC.
To: HANSEN, CHRIS; HANSEN, STEPHANIE
Reel/Frame 045480/0437 →
SECURITY INTEREST Recorded Apr 9, 2018
From: PROVECTUS BIOPHARMACEUTICALS, INC.; PROVECTUS PHARMATECH, INC.; PROVECTUS BIOTECH, INC.; PURE-IFIC, INC.
To: MORRIS, JEFFREY A.
Reel/Frame 045480/0690 →
SECURITY INTEREST Recorded Apr 9, 2018
From: PROVECTUS BIOPHARMACEUTICALS, INC.; PROVECTUS PHARMATECH, INC.; PROVECTUS BIOTECH, INC.; PURE-IFIC, INC.
To: SMITH, GREGORY LYNN
Reel/Frame 045480/0960 →
SECURITY INTEREST Recorded Apr 9, 2018
From: PROVECTUS BIOPHARMACEUTICALS, INC.; PROVECTUS PHARMATECH, INC.; PROVECTUS BIOTECH, INC.; PURE-IFIC, INC.
To: MILLENNIUM TRUST CO. LLC
Reel/Frame 046437/0748 →
SECURITY INTEREST Recorded Aug 9, 2017
From: PROVECTUS PHARMATECH, INC.; PROVECTUS BIOPHARMACEUTICALS, INC.
To: TED R. WATSON REVOCABLE TRUST
Reel/Frame 043244/0210 →
SECURITY INTEREST Recorded Aug 1, 2017
From: PROVECTUS PHARMATECH, INC.; PROVECTUS BIOPHARMACEUTICALS, INC.
To: PATRICIA F. BISCHOFF REVOCABLE TRUST
Reel/Frame 043156/0410 →
SECURITY INTEREST Recorded Jun 26, 2017
From: PROVECTUS PHARMATECH, INC.; PROVECTUS BIOPHARMACEUTICALS, INC.
To: TAUSK, SCOTT A.; TAUSK, SANDRA J.
Reel/Frame 042809/0755 →
SECURITY INTEREST Recorded Apr 21, 2017
From: PROVECTUS PHARMATECH, INC.; PROVECTUS BIOPHARMACEUTICALS, INC.
To: MORRIS, JEFFREY A.
Reel/Frame 042091/0421 →
SECURITY INTEREST Recorded Apr 4, 2017
From: PROVECTUS PHARMATECH, INC.; PROVECTUS BIOPHARMACEUTICALS, INC.
To: WACHTER, ERIC A.; CAL ENTERPRISES LLC
Reel/Frame 042188/0389 →