System and method for predictive ophthalmic correction

1. A system that provides a predictive outcome for a proposed therapeutic ophthalmic correction, comprising:

a collecting and transmitting station for collecting a prospective, therapeutic-outcome-influencing, new information metric relating to at least one of a patient, a practitioner, a diagnostic measurement, a therapeutic condition, and an environmental condition, and for transmitting said plurality of new information to a computing station, wherein said computing station includes means for

a) receiving said new information metric,

b) storing a plurality of optimized historical therapeutic-outcome information derived from an optimization analysis of prospective therapeutic-outcome-influencing, historical information relating to at least one of a patient, a practitioner, a diagnostic measurement, a therapeutic condition, and an environmental condition, and

c) providing an output comprising a predictive best instruction that is derived from an analysis of the new information in conjunction with the optimized historical information to facilitate an improved therapeutic ophthalmic correction.

2. The system of claim 1 , wherein the predictive best instruction is an algorithm that describes a laser ablation shot placement pattern on a patient's eye.

3. The system of claim 1 , wherein the predictive best instruction comprises an outcome-predictive, ophthalmic information metric suited for use by a practitioner for providing the therapeutic ophthalmic correction.

4. The system of claim 1 , wherein the optimization analysis is a statistical analysis.

5. The system of claim 1 , wherein the optimization analysis is a matrix analysis comprising a vector, Z, representing new diagnostic information, a clinical matrix, M′, representing an interdependence relationship of a plurality of Zernike terms or their equivalents, another matrix, M″, representing historical outcome information, and a resultant matrix, Z′, representing the predictive best instruction.

6. The system of claim 5 , further comprising a feedback loop provided by an updating information metric supplied to the matrix M″.

7. The system of claim 5 , wherein the components of M″ represent information from a plurality of sources.

8. The system of claim 5 , wherein the components of Z are Zernike vectors or their equivalents output from a wavefront sensor device.

9. The system of claim 4 , wherein the computing station comprises a data structure employing a neural network for generating the predicted best instruction.

10. The system of claim 1 , wherein the predicted best instruction is a postoperative spherical aberration value, Z 400Post , for a given pupil size.

11. The system of claim 10 , wherein the postoperative spherical aberration value, Z 400Post , is exclusively dependent upon a preoperative spherical aberration value, Z 400Pre , a preoperative defocus value, Z 200Pre , and a constant factor, ±C.

12. The system of claim 11 , wherein Z 400Post =A*Z 400Pre +B*Z 200Pre +C, where A, B are (±) constants for the given pupil size.

13. The system of claim 1 , wherein the computing station is in physical proximity to the collecting and transmitting station.

14. The system of claim 1 , wherein the computing station is located remotely from the collecting and transmitting station.

15. A system that provides a predictive outcome for a therapeutic ophthalmic correction, comprising a computing station having a data structure that contains an optimized historical therapeutic-outcome information metric derived from an optimization analysis of a plurality of prospective therapeutic-outcome-influencing, historical information metrics, wherein the computing station is programmed to receive a plurality of prospective therapeutic-outcome-influencing, new information including at least ophthalmic defect information about a patient, wherein said computing station is further programmed to provide in a suitable form an outcome-predictive best instruction based upon an analysis of the new information in conjunction with the historical outcome information.

16. The system of claim 15 , wherein the data structure comprises a neural network.

17. The system of claim 15 , wherein the outcome-predictive best instruction is an algorithm that describes a laser ablation shot placement pattern on a patient's eye.

18. The system of claim 15 , wherein the outcome-predictive best instruction is a postoperative spherical aberration value, Z 400Post , for a given pupil size.

19. The system of claim 18 , wherein the postoperative spherical aberration value, Z 400Post , is exclusively dependent upon a preoperative spherical aberration value, Z 400pre , a preoperative defocus value, Z 200Pre , and a constant factor, ±C.

20. The system of claim 19 , wherein Z 400Post =A*Z 400Pre +B*Z 200Pre +C, where A, B are (±) constants for the given pupil size.

21. The system of claim 15 , wherein the optimization analysis is a statistical analysis.

22. The system of claim 21 , wherein the optimization analysis is a matrix analysis comprising a vector, Z, representing new diagnostic information, a clinical matrix, M′, representing an interdependence relationship of a plurality of Zernike terms or their equivalents, another matrix, M″, representing historical outcome information, and a resultant matrix, Z′, representing the predictive best instruction.

23. The system of claim 22 , further comprising a feedback loop provided by an updating information metric supplied to the matrix M″.

24. The system of claim 22 , wherein the components of M″ represent information from a plurality of sources.

25. The system of claim 22 , wherein the components of Z are Zernike vectors or their equivalents output from a wavefront sensor device.

26. A system that provides a predictive outcome for a therapeutic ophthalmic correction, comprising:

a) a diagnostic station that acquires a new, ophthalmic information metric from a patient and export the new information metric;

b) a data collection and transfer station cooperatively engaged with the diagnostic station that receives and further exports the new information metric;

c) a computing station communicatively engaged with the data collection and transfer station, said computing station including a data structure containing optimized historical therapeutic-outcome information, programmed to receive and transmit information and to analyze each respective new information metric in conjunction with the optimized historical therapeutic-outcome information and, further, to generate a predictive best instruction; and

d) a therapeutic station cooperatively engaged with the computing station, having a capability to execute the predictive best instruction.

27. The system of claim 26 , wherein the data structure comprises a neural network.

28. The system of claim 26 , wherein the outcome-predictive best instruction is an algorithm that describes a laser ablation shot placement pattern on a patient's eye.

29. The system of claim 26 , wherein the outcome-predictive best instruction is a postoperative spherical aberration value, Z 400Post , for a given pupil size.

30. The system of claim 29 , wherein the postoperative spherical aberration value, Z 400Post , is exclusively dependent upon a preoperative spherical aberration value, Z 400Pre , a preoperative defocus value, Z 200Pre , and a constant factor, ±C.

31. The system of claim 30 , wherein Z 400Post =A*Z 400pre +B*Z 200Pre +C, where A, B are (±) constants for the given pupil size.

32. The system of claim 26 , wherein the optimization analysis is a statistical analysis.

33. The system of claim 32 , wherein the optimization analysis is a matrix analysis comprising a vector, Z, representing new diagnostic information, a clinical matrix, M′, representing an interdependence relationship of a plurality of Zernike terms or their equivalents, another matrix, M″, representing historical outcome information, and a resultant matrix, Z′, representing the predictive best instruction.

34. The system of claim 33 , further comprising a feedback loop provided by an updating information metric supplied to the matrix M″.

35. The system of claim 33 , wherein the components of M″ represent information from a plurality of sources.

36. The system of claim 33 , wherein the components of Z are Zernike vectors or their equivalents output from a wavefront sensor device.

37. A method for providing a predictive outcome for a therapeutic ophthalmic correction, comprising:

a) collecting a therapeutic-outcome-influencing, new information metric including at least ophthalmic defect information about a patient;

b) analyzing said new information in conjunction with a plurality of optimized, historical therapeutic outcome information for the determined ophthalmic defect; and

b) generating, via the computing device, a predictive best instruction for facilitating an optimized outcome of the ophthalmic therapeutic correction.

38. The method of claim 37 , further comprising utilizing the generated predictive best instruction to drive a therapeutic system for providing the ophthalmic correction.

39. The method of claim 37 , wherein the collecting step comprises automatically collecting the new information metric.

40. The method of claim 37 , wherein the generating step comprises a statistical analysis.

41. The method of claim 37 , wherein the generating step comprises calculating a resultant matrix, Z′, representing the predictive best instruction, from a vector, Z, representing the new diagnostic information, a clinical matrix, M′, representing an interdependence relationship of a plurality of Zernike terms or their equivalents, and another matrix, M″, representing the historical outcome information.

42. A method for providing a predictive outcome for a therapeutic ophthalmic correction, comprising:

a) obtaining a new information metric, said new information metric relating to an ophthalmic defect condition of a patient;

b) maintaining a database of optimized, historical ophthalmic outcome information, said ophthalmic outcome information being related to the ophthalmic defect condition; and

c) providing a predictive best instruction for the therapeutic ophthalmic correction, wherein the predictive best instruction is provided on a transactional basis.

43. The method of claim 42 , wherein the step of obtaining a new information metric comprises collecting wavefront aberration data from a wavefront sensor device.

44. The method of claim 42 , wherein the step of maintaining a database of optimized, historical ophthalmic outcome information comprises updating the database with available ophthalmic correction outcome information and optimizing the historical outcome information.

45. The method of claim 42 , wherein optimizing the historical outcome information comprises a statistical analysis of the historical outcome information.

46. The method of claim 45 , wherein optimizing the historical outcome information comprises engaging a neural network to analyze the historical outcome information and the available historical outcome information.

47. The method of claim 42 , wherein the step of maintaining a database of optimized, historical ophthalmic outcome information comprises acquiring new historical outcome information from a third party for a fee.

48. The method of claim 42 , wherein the step of providing a predictive best instruction on a transactional basis comprises receiving a fee or other remuneration.

49. A computer-readable or device-readable medium having stored thereon an executable instruction that is intended to provide a predictive outcome for a therapeutic ophthalmic correction, wherein said instruction is a predicted best instruction that is derived from an analysis of a new information metric relating to an ophthalmic condition of a patient, in conjunction with an optimized, historical, therapeutic-outcome information metric.

50. The medium of claim 49 , wherein the executable instruction is an algorithm that describes a laser ablation shot placement pattern on a patient's eye.

51. The system of claim 49 , wherein the predictive best instruction comprises an outcome-predictive, ophthalmic information metric suited for use by a practitioner for providing the therapeutic ophthalmic correction.

52. A data structure associated with a computing device that generates a predictive best instruction for a therapeutic ophthalmic correction, said data structure performing a method comprising the steps of:

a) receiving a new information metric, said new information metric relating to an ophthalmic defect condition of a patient;

b) maintaining a database of optimized historical ophthalmic outcome information, said ophthalmic outcome information being related to the ophthalmic defect condition; and

c) generating a predictive best instruction for the therapeutic ophthalmic correction.

53. The data structure of claim 52 , wherein the predictive best instruction is provided on a transactional basis.

54. The data structure of claim 53 , wherein the step of providing a predictive best instruction on a transactional basis comprises receiving a fee or other remuneration.

55. The data structure of claim 52 , wherein the step of obtaining a new information metric comprises collecting wavefront aberration data from a wavefront sensor device.

56. The data structure of claim 52 , wherein the step of maintaining a database of optimized, historical ophthalmic outcome information comprises updating the database with available ophthalmic correction outcome information and optimizing the historical outcome information.

57. The data structure of claim 56 , wherein optimizing the historical outcome information comprises a statistical analysis of the historical outcome information.

58. The data structure of claim 56 , wherein optimizing the historical outcome information comprises engaging a neural network to analyze the historical outcome information and the available historical outcome information.

59. The data structure of claim 52 , wherein the step of maintaining a database of optimized, historical ophthalmic outcome information comprises acquiring new historical outcome information from a third party for a fee.

60. The system of claim 1 , wherein the optimization analysis is a finite element analysis (FEA) utilizing a finite element model (FEM), further wherein the FEM is a three-dimensional, anisotropic, nonlinear, viscoelastic layered element.

61. The system of claim 15 , wherein the optimization analysis is a finite element analysis (FEA) utilizing a finite element model (FEM), further wherein the FEM is a three-dimensional, anisotropic, nonlinear, viscoelastic layered element.

62. The system of claim 26 , wherein the optimization analysis is a finite element analysis (FEA) utilizing a finite element model (FEM), further wherein the FEM is a three-dimensional, anisotropic, nonlinear, viscoelastic layered element.

63. The method of claim 37 , wherein the generating step comprises performing a finite element analysis (FEA) utilizing a finite element model (FEM), further wherein the FEM is a three-dimensional, anisotropic, nonlinear, viscoelastic layered element.