Implantable marker with a leadless signal transmitter compatible for use in magnetic resonance devices
A leadless marker for localizing the position of a target within a patient. In one embodiment, the marker includes a casing, a resonating circuit, and a ferromagnetic element. The casing is configured to be positioned at a selected location relative to a target site in the patient; the casing, for example, can be configured to be permanently or semi-permanently implanted into the patient. The resonating circuit has an inductor within the casing comprising a plurality of windings of a conductor, but it does not have external electrical lead lines extending through the casing. The ferromagnetic element is at least partially within the inductor. The ferromagnetic element has a volume such that when the marker is in an imaging magnetic field having a field strength of 1.5 T and a gradient of 3 T/m, then the force exerted on the marker by the imaging magnetic field is not greater than gravitational force exerted on the marker.
1. A lead less marker for localizing the position of a target within a patient, comprising:
a casing configured to be positioned at a selected location relative to a target site in the patient;
a resonating circuit without external electrical lead lines extending through the casing, the resonating circuit having an inductor within the casing comprising a plurality of windings of a conductor; and
a ferromagnetic element at least partially within the inductor, the ferromagnetic element having a volume such that when the marker is in an imaging magnetic field having a field strength of 1.5 T and a gradient of 3 T/m, then force exerted on the marker by the imaging magnetic field is not greater than gravitational force exerted on the marker.
2. The marker of claim 1 wherein (a) the inductor further comprises a capacitor electrically coupled to the conductor, (b) the ferromagnetic element comprises a ferrite rod having a diameter not greater than approximately 0.5 mm, and (c) the casing has an outer diameter not greater than approximately 2 mm.
3. The marker of claim 1 wherein the ferromagnetic element comprises a ferrite rod having a diameter of approximately 0.2 mm-0.7 mm and a length of approximately 2 mm-12 mm.
4. The marker of claim 1 wherein the ferromagnetic element comprises a ferrite rod having a volume of approximately 0.5 mm3-19.0 mm3.
5. The marker of claim 1 wherein the ferromagnetic element comprises a ferrite rod and the volume of the rod is less than a volume of ferrite that produces an artifact of 1500 mm2 in an image produced by a resonating magnetic field of approximately 1.5 T.
6. The marker of claim 1 wherein the ferromagnetic element comprises a ferrite rod and the volume of the rod is less than a volume of ferrite that produces an artifact of 400 mm2-1200 mm2 in an image produced by a resonating magnetic field of approximately 1.5 T.
7. The marker of claim 1 wherein (a) the ferromagnetic element comprises a ferrite rod having a diameter of approximately 0.2 mm-0.7 mm, (b) the windings comprise a coil having an inner diameter of approximately 0.2 mm-0.8 mm and an outer diameter of approximately 0.8 mm-1.9 mm, and (c) the casing has an outer diameter of approximately 1.0 mm-2.5 mm.
8. The marker of claim 1 wherein (a) the ferromagnetic element comprises a ferrite rod having a diameter of approximately 0.3 mm-0.5 mm, (b) the windings comprise a coil having an inner diameter of approximately 0.3 mm-0.6 mm and an outer diameter of approximately 1.2 mm-1.9 mm, and (c) the casing has an outer diameter of approximately 2 mm.
9. The marker of claim 1 wherein (a) the inductor further comprises a capacitor at one end of the ferromagnetic element which is electrically coupled to the conductor, and (b) the marker further comprises a module at the other end of the capacitor which is symmetrical with respect to the capacitor.
10. A leadless implantable marker for localizing the position of a target within a patient, comprising:
a casing configured to be permanently implanted in the patient;
a ferromagnetic element in the casing, the ferromagnetic element having a volume such that when the marker is in an imaging magnetic field having a field strength of 1.5 T and a gradient of 3 T/m, then force exerted on the marker by the magnetic field is not greater than gravitational force exerted on the marker; and
a resonating circuit without external electrical lead lines extending through the casing, the resonating circuit having an inductor within the casing comprising a plurality of windings of a conductor around at least a portion of the ferromagnetic element, wherein the resonating circuit is configured to be energized by an excitation magnetic field and produce a response signal for identifying the position of the marker relative to a reference sensor assembly.
11. The marker of claim 10 wherein (a) the inductor further comprises a capacitor electrically coupled to the conductor, (b) the ferromagnetic element comprises a ferrite rod having a diameter not greater than approximately 0.5 mm, and (c) the casing has an outer diameter not greater than approximately 2 mm.
12. The marker of claim 10 wherein the ferromagnetic element comprises a ferrite rod having a diameter of approximately 0.2 mm-0.7 mm and a length of approximately 2 mm-12 mm.
13. The marker of claim 10 wherein the ferromagnetic element comprises a ferrite rod and the volume of the rod is less than a volume of ferrite that produces an artifact of 1500 mm2 in an image produced by a resonating magnetic field of approximately 1.5 T.
14. The marker of claim 10 wherein the ferromagnetic element comprises a ferrite rod and the volume of the rod is less than a volume of ferrite that produces an artifact of 400 mm2-1200 mm2 in an image produced by a resonating magnetic field of approximately 1.5 T.
15. The marker of claim 10 wherein (a) the ferromagnetic element comprises a ferrite rod having a diameter of approximately 0.2 mm-0.7 mm, (b) the windings comprise a coil having an inner diameter of approximately 0.2 mm-0.8 mm and an outer diameter of approximately 1.2 mm-1.9 mm, and (c) the casing has an outer diameter of approximately 1.5 mm-2.5 mm.
16. The marker of claim 10 wherein (a) the inductor further comprises a capacitor at one end of the ferromagnetic element which is electrically coupled to the conductor, and (b) the marker further comprises a module at the other end of the ferromagnetic element which is symmetrical with respect to the capacitor.
17. A wireless implantable marker for localizing the position of a target within a patient, comprising:
a ferromagnetic core having a length and a cross-sectional dimension normal to the length, wherein the cross-sectional dimension is not greater than 0.7 mm;
a resonating circuit comprising a conductive element having a plurality of windings surrounding at least a portion of the ferromagnetic core, wherein the resonating circuit is not coupled to external electrical leads; and
a casing around the ferromagnetic core and the resonating circuit.
18. The implantable marker of claim 17 , wherein the casing has a cross-sectional dimension normal to the length of the ferromagnetic core not greater than approximately 2.5 mm.
19. The implantable marker of claim 17 , wherein the ferromagnetic core has cross-sectional dimension defined by a diameter of approximately 0.25 mm to 0.65 mm.
20. The marker of claim 17 wherein (a) the resonating circuit further comprises a capacitor at one end of the ferromagnetic core which is electrically coupled to the conductive element, and (b) the marker further comprises a module at the other end of the ferromagnetic core which is symmetrical with respect to the capacitor.
21. A wireless implantable marker for localizing the position of a target within a patient, comprising:
a ferromagnetic core having an outer diameter not greater than approximately 0.7 mm;
a coil having windings positioned around at least a portion of the core; and
a casing around the core and the coil without external electrical leads projecting from the casing.
22. The marker of claim 21 wherein (a) a capacitor is electrically coupled to the coil, (b) the ferromagnetic core comprises a ferrite rod having a diameter not greater than approximately 0.5 mm, and (c) the casing has an outer diameter not greater than approximately 2 mm.
23. The marker of claim 21 wherein the ferromagnetic core comprises a ferrite rod having a diameter of approximately 0.2 mm-0.7 mm and a length of approximately 2 mm-12 mm.
24. The marker of claim 21 wherein the ferromagnetic core comprises a ferrite rod and the volume of the rod is less than a volume of ferrite that produces an artifact of 1500 mm2 in an image produced by a magnetic resonance imager magnetic field of approximately 1.5 T.
25. The marker of claim 21 wherein (a) a capacitor is coupled to the coil and positioned at one end of the ferromagnetic core, and (b) the marker further comprises a module at the other end of the ferromagnetic core which is symmetrical with respect to the capacitor.
26. A leadless implantable marker for localizing the position of a target within a patient, comprising:
a ferromagnetic core having a volume that produces an image artifact not greater than 1500 mm2 in an image from a magnetic resonance device using a magnetic field strength of 1.5 T and a gradient of 3 T/m;
a resonating circuit comprising a conductive element having a plurality of windings surrounding at least a portion of the ferromagnetic core, wherein the resonating circuit is not coupled to external electrical leads; and
a casing enclosing the core and the resonating circuit.
27. The marker of claim 26 wherein (a) the resonating circuit further comprises a capacitor electrically coupled to the conducting element, (b) the ferromagnetic core comprises a ferrite rod having a diameter not greater than approximately 0.5 mm, and (c) the casing has an outer diameter not greater than approximately 2 mm.
28. The marker of claim 26 wherein the ferromagnetic core comprises a ferrite rod having a diameter of approximately 0.2 mm-0.7 mm and a length of approximately 2 mm-12 mm.
29. The marker of claim 26 wherein the ferromagnetic core comprises a ferrite rod having a volume of approximately 0.5 mm3-19.0 mm3.
30. The marker of claim 26 wherein (a) the ferromagnetic core comprises a ferrite rod having a diameter of approximately 0.2 mm-0.7 mm, (b) the windings comprise a coil having an inner diameter of approximately 0.2 mm-0.8 mm and an outer diameter of approximately 1.2 mm-1.9 mm, and (c) the casing has an outer diameter of approximately 1.5 mm-2.5 mm.
31. The marker of claim 26 wherein (a) the ferromagnetic core comprises a ferrite rod having a diameter of approximately 0.3 mm-0.5 mm, (b) the windings comprise a coil having an inner diameter of approximately 0.3 mm-0.6 mm and an outer diameter of approximately 1.2 mm-1.9 mm, and (c) the casing has an outer diameter of approximately 2 mm.
32. The marker of claim 26 wherein (a) the resonating circuit further comprises a capacitor at one end of the ferromagnetic core which is electrically coupled to the conductive element, and (b) the marker further comprises a module at the other end of the ferromagnetic core which is symmetrical with respect to the capacitor.
33. A leadless implantable marker for localizing the position of a target within a patient, comprising:
a ferromagnetic element having a first end and a second end;
a resonating circuit comprising an inductor having a plurality of windings of a conductor surrounding at least a portion of the ferromagnetic element and a capacitor at the first end of the ferromagnetic element;
a module at the second end of the ferromagnetic element, the module being symmetrical relative to the capacitor; and
a casing around the ferromagnetic element, the resonating circuit and the module.
34. The marker of claim 33 wherein (a) the ferromagnetic element comprises a ferrite rod having a diameter not greater than approximately 0.7 mm, and (b) the casing has an outer diameter not greater than approximately 2 mm.
35. The marker of claim 33 wherein the ferromagnetic element comprises a ferrite rod having a diameter of approximately 0.2 mm-0.5 mm and a length of approximately 2 mm-12 mm.
36. The marker of claim 33 wherein the ferromagnetic element comprises a ferrite rod having a volume of approximately 0.5 mm3-19.0 mm3.
37. The marker of claim 33 wherein the ferromagnetic element comprises a ferrite rod and the volume of the rod is less than a volume of ferrite that produces an artifact of 1500 mm2 in an image produced by a resonating magnetic field of approximately 1.5 T.
38. The marker of claim 33 wherein the ferromagnetic element comprises a ferrite rod and the volume of the rod is less than a volume of ferrite that produces an artifact of 400 mm2-1200 mm2 in an image produced by a resonating magnetic field of approximately 1.5 T.
39. The marker of claim 33 wherein (a) the ferromagnetic element comprises a ferrite rod having a diameter of approximately 0.2 mm-0.6 mm, (b) the windings comprise a coil having an inner diameter of approximately 0.2 mm-0.8 mm and an outer diameter of approximately 1.2 mm-1.9 mm, and (c) the casing has an outer diameter of approximately 1.5 mm-2.5 mm.
40. The marker of claim 33 wherein (a) the ferromagnetic element comprises a ferrite rod having a diameter of approximately 0.3 mm-0.5 mm, (b) the windings comprise a coil having an inner diameter of approximately 0.3 mm-0.6 mm and an outer diameter of approximately 1.2 mm-1.9 mm, and (c) the casing has an outer diameter of approximately 2 mm.
41. The marker of claim 1 wherein the inductor further comprises a capacitor at one end of the ferromagnetic element which is electrically coupled to the conductor, and wherein the method further comprises providing a module at the other end of the ferromagnetic element which is symmetrical with respect to the capacitor.