IP Library › Granted Patent US 7,014,854
Granted Patent B2
US 7,014,854 · App. 10/334,701 · Granted Mar 21, 2006

Method for retarding or precluding Alzheimer's dementia

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Quick Facts
Patent No.
US 7,014,854
App. No.
10/334,701
Granted
Mar 21, 2006
Kind
B2
Abstract

A method for treating a condition related to the development of Alzheimer's disease (AD) is disclosed. The method involves the removal of circulating autoantibodies of a biochemical marker or markers, specifically human glial fibrillary acidic protein (GFAP) and glyceraldehyde-3-phosphate dehydrogenase (GAPDH), from the sera of a patient in an amount effective to reduce or eliminate phagocytosis of astrocytic cells. The invention further includes a process of immune system modulation effective for autoantibody removal.

Claims (3)

1. A process for retarding phagocytosis of astrocytic cells comprising:

determining the presence in body fluid of autoantibodies against glial fibrillary acidic protein (GFAP); and

removing said autoantibodies from said body fluid whereby said removing retards phagocytosis of astrocytic cells.