Manufacturing processes for making optical analysis discs including successive patterning operations and optical discs thereby manufactured
A manufacturing process for optical analysis discs including successive patterning operations and a related optical analysis discs thereby manufactured. The process includes providing a planar substrate layer, patterning on the planar substrate layer a spacing material forming a fluidic cavity configuration, and providing a cover layer bonded onto the planar substrate layer containing the fluidic cavity configuration. The optical analysis disc includes a planar substrate layer, a fluidic cavity configuration formed on the planar substrate layer by patterning a spacing adhesive material, and a cover layer bonded onto the planar substrate layer containing the fluidic cavity configuration.
1 . Manufacturing process for optical analysis discs including the steps of:
providing a planar substrate layer;
patterning on said planar substrate layer a spacing material forming a fluidic cavity configuration; and
providing a cover layer bonded onto said planar substrate layer containing said fluidic cavity configuration.
2 . The manufacturing process for optical analysis discs according to claim 1 wherein said spacing material includes a curable material in a plurality of strips to form grooves after curing.
3 . The manufacturing process for optical analysis discs according to claim 2 wherein the strips of curable material are placed to form fluidic channel sidewalls.
4 . The manufacturing process for optical analysis discs according to claim 2 wherein the strips of curable material are placed to form bonding grooves, the process comprising the further step of filling up said bonding grooves by a deposition of adhesive material.
5 . The manufacturing process for optical analysis discs according to claim 4 wherein said adhesive material is deposited by a printing technique.
6 . The manufacturing process for optical analysis discs according to claim 5 wherein said printing technique is a silk screening printing.
7 . The manufacturing process for optical analysis discs according to claim 2 wherein said curable material is a polymer.
8 . The manufacturing process for optical analysis discs according to claim 1 comprising the further step of depositing capturing chemistry on said planar substrate layer at said fluidic cavity configuration before bonding said cover layer onto the planar substrate layer.
9 . The manufacturing process for optical analysis discs according to claim 1 comprising a step of depositing adhesive material on said planar substrate layer to bond the cover layer onto said planar substrate layer.
10 . The manufacturing process for optical analysis discs according to claim 9 wherein said adhesive material is deposited by a printing technique.
11 . The manufacturing process for optical analysis discs according to claim 10 wherein said printing technique is a silk screening printing.
12 . An optical analysis disc obtained by a manufacturing process for optical analysis discs, the disc comprising:
a planar substrate layer;
a fluidic cavity configuration formed on said planar substrate layer by patterning a spacing material; and
a cover layer bonded onto said planar substrate layer containing said fluidic cavity configuration.
13 . The optical analysis disc according to claim 12 wherein said spacing material includes a curable material patterned in a plurality of strips to form grooves after curing.
14 . The optical analysis disc according to claim 12 wherein said spacing material includes a curable material patterned in strips to form fluidic channel sidewalls.
15 . The optical analysis disc according to claim 12 wherein said fluidic cavity configuration includes bonding grooves filled by a deposition of adhesive material.
16 . The optical analysis disc according to claim 15 wherein said adhesive material is deposited by a printing technique.
17 . The optical analysis disc according to claim 16 wherein said printing technique is a silk screening printing.
18 . The optical analysis disc according to claim 13 wherein said curable material is a polymer.
19 . The optical analysis disc according to claim 12 further comprising capturing chemistry on said planar substrate layer at said fluidic cavity configuration.
20 . The optical analysis disc according to claim 12 further comprising adhesive material deposited on said planar substrate layer to bond the cover layer onto said planar substrate layer.
21 . The optical analysis disc according to claim 20 wherein said adhesive material is deposited by a printing technique.
22 . The optical analysis disc according to claim 21 wherein said printing technique is a silk screening printing.
23 . A manufacturing process for making optical analysis discs, said method comprising the steps of:
providing a planar substrate layer;
patterning on said planar substrate layer a spacing curable material forming a fluidic cavity configuration including bonding grooves and fluidic channels delimited by respective sidewalls;
filling said bonding grooves with adhesive material; and
providing a cover layer bonded onto said planar substrate layer containing said fluidic cavity configuration.
24 . The manufacturing process for making optical analysis discs according to claim 23 wherein said curable spacing material is a polymer.
25 . The manufacturing process for making optical analysis discs according to claim 23 wherein said adhesive material is deposited into said bonding grooves by a printing technique.
26 . The manufacturing process for making optical analysis discs according to claim 25 wherein said printing technique is a silk screening printing.
27 . The manufacturing process for making optical analysis discs according to claim 23 comprising a step of depositing capturing chemistry on said planar substrate layer at said fluidic cavity configuration before bonding said cover layer onto the planar substrate layer.
28 . The manufacturing process for making optical analysis discs according to claim 23 comprising a step of depositing adhesive material on said planar substrate layer to bond the cover layer onto said planar substrate layer.
29 . The manufacturing process for making optical analysis discs according to claim 28 wherein said adhesive material is deposited by a printing technique.
30 . The manufacturing process for making optical analysis discs according to claim 29 wherein said printing technique is a silk screening printing.
31 . An optical analysis disc obtained by a manufacturing process for optical analysis discs, the disc comprising:
a planar substrate layer;
a fluidic cavity configuration formed on said planar substrate layer, having bonding grooves and fluidic channels delimited by respective sidewalls, said bonding grooves and said sidewalls being both obtained by patterning a spacing curable material, said bonding grooves being filled with a deposition of adhesive material; and
cover layer bonded onto said planar substrate layer containing said fluidic cavity configuration.
32 . The optical analysis disc according to claim 31 wherein said curable spacing material is a polymer.
33 . The optical analysis disc according to claim 31 wherein said adhesive material is deposited into said bonding grooves by a printing technique.
34 . The optical analysis disc according to claim 33 wherein said printing technique is a silk screening printing.
35 . The optical analysis disc according to claim 31 further comprising capturing chemistry on said planar substrate layer at said fluidic cavity configuration.
36 . The optical analysis disc according to claim 31 further comprising adhesive material deposited on said planar substrate layer to bond the cover layer onto said planar substrate layer.
37 . The optical analysis disc according to claim 36 wherein said adhesive material is deposited by a printing technique.
38 . The optical analysis disc according to claim 37 wherein said printing technique is a silk screening printing.
39 . A manufacturing process for optical analysis discs, said method comprising the steps of:
providing a planar substrate layer;
patterning on said planar substrate layer a spacing adhesive material forming a fluidic cavity configuration; and
providing a cover layer bonded onto said planar substrate layer containing said fluidic cavity configuration.
40 . The manufacturing process for optical analysis discs according to claim 39 wherein said adhesive material is patterned by a printing technique.
41 . The manufacturing process for optical analysis discs according to claim 40 wherein said printing technique is a silk screening printing.
42 . The manufacturing process for optical analysis discs according to claim 39 comprising a step of depositing capturing chemistry on said planar substrate layer at said fluidic cavity configuration before bonding said cover layer onto the planar substrate layer.
43 . The optical analysis disc obtained by a manufacturing process for optical analysis discs, the disc comprising:
a planar substrate layer;
a fluidic cavity configuration formed on said planar substrate layer by patterning a spacing adhesive material; and
a cover layer bonded onto said planar substrate layer containing said fluidic cavity configuration.
44 . The optical analysis disc according to claim 43 wherein said adhesive material is patterned by a printing technique.
45 . The optical analysis disc according to claim 44 wherein said printing technique is a silk screening printing.
46 . The optical analysis disc according to claim 43 further comprising capturing chemistry on said planar substrate layer at said fluidic cavity configuration.