Ischemia laser treatment
View Patent ↗Apparatus for treatment of an ischemic region of brain cells in a cranium, comprising a skull covering adapted to cover at least part of the cranium, at least one guide attached to the skull covering, and a laser source which is operative to direct a laser beam through the at least one guide into the cranium. The at least one guide may include an optic filiter or a waveguide.
1. A therapy apparatus for treating brain tissue, the therapy apparatus comprising:
a skull covering adapted to cover at least a portion of a patient's cranium;
said skull covering including at least one light source; and
a controller operatively connected to the light source and controlling operation of the light source;
wherein said at least one light source is positioned to irradiate a portion of a patient's cranium with light having a wavelength and power density sufficient to:
penetrate the patient's skull; and
deliver an efficacious amount of light to brain tissue to treat brain cells following ischemic stroke in a patient thereby producing a cytoprotective effect and an increase in survival of neurons.
2. The apparatus of claim 1 , wherein the light source is a laser source.
3. The apparatus of claim 1 , wherein the light source is moveable with respect to the cranium.
4. The apparatus of claim 1 , further comprising an actuator operative to move the light source further from or closer to the cranium.
5. The apparatus of claim 1 , wherein the light source is attached to a plurality of guides such that light from the source passes through the guides.
6. The apparatus of claim 1 , wherein the light source has a wavelength of about 807 nm.
7. The apparatus of claim 1 , wherein the light source delivers a power density of about 8 mW/cm 2 to brain tissue.
8. The apparatus of claim 1 , wherein the apparatus comprises two or more light sources.
9. Apparatus for treatment of an ischemic region of brain cells in a cranium, comprising:
a skull covering adapted to cover at least part of a cranium;
at least one guide attached to said skull covering;
a laser source operative to direct a laser beam through said at least one guide into a cranium; and
a controller operatively connected to the laser source and controlling operation of the laser source;
wherein said light source produces light having a wavelength and power density sufficient to:
penetrate the patient's skull; and
deliver an efficacious amount of light to brain tissue to cause biostimulation of brain cells following ischemic stroke.
10. The apparatus according to claim 9 wherein said at least one guide comprises an optic fiber.
11. The apparatus according to claim 9 wherein said at least one guide comprises a waveguide.
12. The apparatus according to claim 9 comprising a plurality of said guides attached to said skull covering which direct a plurality of laser beams in a plurality of directions.
13. The apparatus according to claim 9 comprising a plurality of said guides attached to said skull covering which focus a plurality of laser beams in a plurality of focal lengths into a cranium.
14. The apparatus according to claim 9 comprising a plurality of said guides which are commonly attached to said laser source.
15. The apparatus according to claim 9 comprising a plurality of said laser sources and a plurality of said guides, wherein each source directs a laser beam through one said guide.
16. A method of treating brain tissue, the method comprising:
identifying a patient whose brain has at least one ischemic portion; and
irradiating at least a portion of the cranium of said patient with light;
wherein said irradiating is performed through the skull
wherein said light has a wavelength and power density sufficient to penetrate the skull; and
cause biostimulation of brain cells and increased neuron survival following an ischemic event.
17. The method according to claim 16 , wherein the wavelength is about 807 nm.
18. The method according to claim 16 , wherein the power density is selected to provide a power density of about 5 mW/cm 2 to about 8 mW/cm 2 to the brain tissue.
19. The method according to claim 16 , wherein the light has a protective effect on the brain cells.
20. The method according to claim 16 , wherein the light causes a regeneration process in the injured brain cells.