IP Library › Granted Patent US 6,960,558
Granted Patent B2
US 6,960,558 · App. 10/356,191 · Granted Nov 1, 2005

Method of screening for anti-obesity agents using ciliary neutrophic factor receptor

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Quick Facts
Patent No.
US 6,960,558
App. No.
10/356,191
Granted
Nov 1, 2005
Kind
B2
Abstract

The present invention relates to methods for screening for anti-obesity agents using the ciliary neutrophic factor receptor.

Claims (6)

1. A method of screening for an anti-obesity agent comprising the steps of:

(a) identifying a compound that binds the ciliary neurotrophic factor receptor; and

(b) measuring the ability of said compound to reduce body weight using an animal model for measuring obesity, whereby said compound is identified as said anti-obesity agent if said compound causes a reduction in body weight.

2. The method of claim 1 , wherein said animal model is a genetically obese mouse.

3. The method of claim 1 , wherein said animal model is a mouse with diet-induced obesity.

4. The method of claim 1 , further comprising step (c) wherein the ability of said anti-obesity agent in combination with leptin to reduce body weight is measured using said animal model.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 21, 2014
From: ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A.
To: MSD ITALIA S.R.L.
Reel/Frame 032720/0243 →