IP Library Granted Patent US 7,029,449
Granted Patent B2
US 7,029,449 · App. 10/356,602 · Granted Apr 18, 2006

Arteriosclerosis inspecting apparatus

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Quick Facts
Patent No.
US 7,029,449
App. No.
10/356,602
Granted
Apr 18, 2006
Kind
B2
Abstract

An arteriosclerosis inspecting apparatus including an information obtaining device which obtains information that is related to a velocity at which a pulse wave propagates in a living subject, a blood-pressure measuring device which measures a blood pressure of the subject, a heart-rate measuring device which measures a heart rate of the subject, a pre-ejection-period measuring device which measures a pre-ejection period from a time of starting of contraction of the heart of the subject to a time of starting of ejection of blood from the heart, an ejection-time measuring device which measures an ejection time from the time of starting of ejection of blood from the heart to a time of ending of ejection of blood from the heart, and an arteriosclerosis-inspection-related-augmentation-index determining means for determining an arteriosclerosis-inspection-related augmentation index of the subject, based on the obtained pulse-wave-velocity-related information, the measured blood pressure, the measured heart rate, the measured pre-ejection period, and the measured ejection time, according to a predetermined relationship between (A) (a1) pulse-wave-velocity-related information, (a2) blood pressure, (a3) heart rate, (a4) pre-ejection period and (a5) ejection time, and (B) arteriosclerosis-inspection-related augmentation index.

Claims (40)

1. An apparatus for inspecting arteriosclerosis of a living subject, comprising:

a pulse-wave-velocity-related-information obtaining device which obtains pulse-wave-velocity-related information that is related to a velocity at which a pulse wave propagates in the subject;

a blood-pressure measuring device which measures a blood pressure of the subject;

a heart-rate measuring device which measures a heart rate of the subject;

a pre-ejection-period measuring device which measures a pre-ejection period from a time of starting of contraction of the heart of the subject to a time of starting of ejection of blood from the heart;

an ejection-time measuring device which measures an ejection time from the time of starting of ejection of blood from the heart to a time of ending of ejection of blood from the heart; and

an arteriosclerosis-inspection-related-augmentation-index determining means for determining an arteriosclerosis-inspection-related augmentation index of the subject, based on the pulse-wave-velocity-related information obtained by the pulse-wave-velocity-related-information obtaining device, the blood pressure measured by the blood-pressure measuring device, the heart rate measured by the heart-rate measuring device, the pre-ejection period measured by the pre-ejection-period measuring device, and the ejection time measured by the ejection-time measuring device, according to a predetermined relationship between (A) (a1) pulse-wave-velocity-related information, (a2) blood pressure, (a3) heart rate, (a4) pre-ejection period and (a5) ejection time, and (B) arteriosclerosis-inspection-related augmentation index.

2. An apparatus according to claim 1 , wherein the predetermined relationship is represented by a following expression:

AI E =a×PWV+b×BP+c×HR+d×ET+e×PEP+f

where PWV is pulse-wave-velocity-related information,

BP is blood pressure,

HR is heart rate,

PEP is pre-ejection period

ET is ejection time,

AI E is arteriosclerosis-inspection-related augmentation index,

a, b, c, d, and e are coefficients, and

f is a constant.

3. An apparatus according to claim 1 , further comprising a display device which displays the arteriosclerosis-inspection-related augmentation index of the subject determined by the arteriosclerosis-inspection-related-augmentation-index determining means.

4. An apparatus according to claim 2 , wherein the predetermined relationship is predetermined for each living subject, and wherein the apparatus further comprises a display device which displays the coefficients a, b, c, d, and e and the constant f of the predetermined relationship.

5. An apparatus according to claim 1 , further comprising a memory device which stores the predetermined relationship.

6. An apparatus for inspecting arteriosclerosis of a living subject, comprising:

an augmentation-index measuring device which measures an augmentation index of the subject that is a proportion of a magnitude of a reflected-wave component of a pulse wave of the subject to a magnitude of an incident-wave component of the pulse wave;

a blood-pressure measuring device which measures a blood pressure of the subject;

a heart-rate measuring device which measures a heart rate of the subject;

a pre-ejection-period measuring device which measures a pre-ejection period from a time of starting of contraction of the heart of the subject to a time of starting of ejection of blood from the heart;

an ejection-time measuring device which measures an ejection time from the time of starting of ejection of blood from the heart to a time of ending of ejection of blood from the heart; and

an arteriosclerosis-inspection-related-pulse-wave-velocity-related-value determining means for determining an arteriosclerosis-inspection-related pulse-wave-velocity-related value of the subject, based on the augmentation index measured by the augmentation-index measuring device, the blood pressure measured by the blood-pressure measuring device, the heart rate measured by the heart-rate measuring device, the pre-ejection period measured by the pre-ejection-period measuring device, and the ejection time measured by the ejection-time measuring device, according to a predetermined relationship between (A) (a1) augmentation index, (a2) blood pressure, (a3) heart rate, (a4) pre-ejection period and (a5) ejection time, and (B) arteriosclerosis-inspection-related pulse-wave-velocity-related value.

7. An apparatus according to claim 6 , wherein the predetermined relationship is represented by a following expression:

PWV E =a′×AI+b′×BP+c′×HR+d′×ET+e′×PEP+f′

where PWV E is arteriosclerosis-inspection-related pulse-wave-velocity-related value,

BP is blood pressure,

HR is heart rate,

PEP is pre-ejection period

ET is ejection time,

AI is augmentation index,

a′, b′, c′, d′, and e′ are coefficients, and

f′ is a constant.

8. An apparatus according to claim 6 , further comprising a display device which displays the arteriosclerosis-inspection-related pulse-wave-velocity-related value of the subject determined by the arteriosclerosis-inspection-related-pulse-wave-velocity-related-value determining means.

9. An apparatus according to claim 7 , wherein the predetermined relationship is predetermined for each living subject, and wherein the apparatus further comprises a display device which displays the coefficients a′, b′, c′, d′, and e′ and the constant f′ of the predetermined relationship.

10. An apparatus according to claim 6 , further comprising a pulse-wave detecting device which detects the pulse wave from the subject.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 10, 2004
From: COLIN CORPORATION
To: COLIN MEDICAL TECHNOLOGY CORPORATION
Reel/Frame 014420/0448 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 3, 2003
From: OGURA, TOSHIHIKO
To: COLIN CORPORATION
Reel/Frame 013728/0588 →