Inhibitors of histone deacetylase
View Patent ↗The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
1. A histone deacetylase inhibitor of formula (1):
or a pharmaceutically acceptable salt thereof.
2. A composition comprising a compound according to claim 1 and a pharmaceutically acceptable carrier.
3. A method of inhibiting histone deacetylase in a cell, the method comprising contacting a cell with a compound according to claim 1 , in an amount sufficient to inhibit histone deacetylase.
4. A method of inhibiting histone deacetylase in a cell, the method comprising contacting a cell with a composition according to claim 2 , in an amount sufficient to inhibit histone deacetylase.