IP Library Granted Patent US 39,347
Granted Patent E1
US 39,347 · App. 10/358,830 · Granted Oct 17, 2006

Multiple layer softgel

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Quick Facts
Patent No.
US 39,347
App. No.
10/358,830
Granted
Oct 17, 2006
Kind
E1
Abstract

A device, and a method for forming a softgel having multiple gelatin layers and softgels having multiple gelatin layers are disclosed. In particular there is provided a device for forming a gelatin sheet having at least two gelatin layers. Each gelatin layer has a thickness. The device comprises a gelatin spreader box which includes at least one opening for extruding a gelatin sheet. The device also includes a first and a second height adjustable gate disposed at least partially across the opening; and a first and a second height adjustment control. Adjustment of the first height adjustment control varies the height of the first gate and adjustment of the second height adjustment control varies the height of the second gate, thereby controlling the thickness of the at least two gelatin layers.

Claims (48)

1. A softgel capsule with content, having opposing ends comprising a first sheet that covers a first end, the first sheet comprising at least a first gelatin layer and a second gelatin layer, each layer having a uniform thickness, and a second sheet that covers a second end, the second sheet comprising at least a third gelatin layer, the third layer having a uniform thickness wherein the first and second sheets meet at a seam.

2. The softgel capsule of claim 1 further comprising a fourth gelatin layer that surrounds the third layer.

3. The softgel capsule of claim 2 wherein the first layer is adjacent the second layer and the third layer is adjacent the fourth layer.

4. The softgel capsule of claim 2 wherein the first and third layers are a first color and the second and fourth layers are a second color.

5. The softgel capsule of claim 2 wherein the first and third layers are colored and the second and fourth layers are uncolored.

6. The softgel capsule of claim 1 wherein the thickness of the first and second gelatin layers are the same.

7. The softgel capsule of claim 1 wherein the thickness of the first and second gelatin layers are different.

8. The softgel capsule of claim 1 wherein the first and second layers differ with respect to at least one property selected from the group consisting of degree of permeability, rate of dissolution, mouth feel and taste.

9. The softgel capsule of claim 1 formed by an apparatus comprising a device for forming the first sheet having at least two gelatin layers.

10. A softgel having two opposing ends divided at a seam having at least one sheet covering each end, the at least one sheet comprising at least two stacked gelatin layers of uniform thickness.

11. The softgel of claim 1 wherein the combined thickness of the first and second layers is approximately equal to the thickness of the third layer.

12. The softgel capsule of claim 2 wherein the first and third layers are uncolored and the second and fourth layers are colored.

13. The softgel capsule of claim 2 wherein the first and third layers are a cellulose derivative and gelatin mixture and the second and fourth layers are gelatin.

14. The softgel capsule of claim 13 wherein the first and third layers are comprised of from about 1% to about 10% cellulose acetate phthalate.

15. The softgel capsule of claim 2 wherein the first and second sheets respectively further comprise a fifth layer surrounding the first layer and a sixth layer surrounding the third layer.

16. The softgel capsule of claim 15 wherein the second, fourth, fifth, and sixth layers are gelatin and the first and third layers are a cellulose derivative.

17. The softgel of claim 2 wherein the thickness of the third and fourth layers is the same.

18. The softgel of claim 2 wherein the thickness of the third and fourth layers is different.

19. The softgel of claim 1 wherein the first and third layers are colored and the second layer is uncolored.

20. A softgel capsule having opposing ends comprising:

a first sheet having at least a first gelatin layer that surrounds a second gelatin layer; and

a second sheet having at least a third gelatin layer that surrounds a fourth gelatin layer,

wherein the first and second sheets cover respective opposing ends of the softgel capsule and fuse together to form a seam.

21. The softgel capsule of claim 20 wherein the combined thickness of the first and second layers is about equal to combined thickness of the third and fourth layers.

22. The softgel capsule of claim 20 wherein the thickness of each layer is the same.

23. The softgel of claim 20 wherein the thickness of each layer is different.

24. The softgel of claim 20 wherein the first, third, and fourth layers are uncolored and the second layer is colored.

25. The softgel of claim 20 wherein the first and third layers are uncolored and the second and fourth layers are colored.

26. A softgel capsule with content, having opposing ends comprising a first sheet that covers a first end, the first sheet comprising at least a first layer and a second layer, each layer having a substantially uniform thickness, and a second sheet that covers a second end, the second sheet comprising at least a third layer and a fourth layer that surrounds the third layer, the third and fourth layers each having a substantially uniform thickness, wherein the first and second sheets meet at a seam, and wherein at least one of the layers comprises cellulose acetate phthalate.

27. A softgel capsule with content, having opposing ends comprising a first sheet that covers a first end, the first sheet comprising at least a first layer and a second layer, each layer having a substantially uniform thickness, and a second sheet that covers a second end, the second sheet comprising at least a third layer and a fourth layer that surrounds the third layer, the third and fourth layers each having a substantially uniform thickness, wherein the first and second sheets meet at a seam, and wherein at least one of the layers comprises methyl cellulose.

28. A softgel capsule with content, having opposing ends comprising a first sheet that covers a first end, the first sheet comprising at least a first layer and a second layer, each layer having a substantially uniform thickness, and a second sheet that covers a second end, the second sheet comprising at least a third layer and a fourth layer that surrounds the third layer, the third and fourth layers each having a substantially uniform thickness, wherein the first and second sheets meet at a seam, and wherein at least one of the layers comprises ethyl cellulose.

29. A softgel capsule with content, having opposing ends comprising a first sheet that covers a first end, the first sheet comprising at least a first layer and a second layer, each layer having a substantially uniform thickness, and a second sheet that covers a second end, the second sheet comprising at least a third layer and a fourth layer that surrounds the third layer, the third and fourth layers each having a substantially uniform thickness, wherein the first and second sheets meet at a seam, and wherein at least one of the layers comprises hydroxypropylmethyl cellulose.

30. The softgel capsule of claim 26 wherein the first and third layers comprise cellulose acetate phthalate.

31. The softgel capsule of claim 27 wherein the first and third layers comprise methyl cellulose.

32. The softgel capsule of claim 28 wherein the first and third layers comprise ethyl cellulose.

33. The softgel capsule of claim 29 wherein the first and third layers comprise hydroxypropylmethyl cellulose.

34. The softgel capsule of claim 27 wherein the second and fourth layers comprise methyl cellulose.

35. The softgel capsule of claim 28 wherein the second and fourth layers comprise ethyl cellulose.

36. The softgel capsule of claim 29 wherein the second and fourth layers comprise hydroxypropylmethyl cellulose.

37. The softgel capsule of claim 26 wherein the first and second sheets respectively further comprise a fifth layer surrounding the first layer and a sixth layer surrounding the third layer, and wherein at least one of the layers comprises cellulose acetate phthalate.

38. The softgel capsule of claim 27 wherein the first and second sheets respectively further comprise a fifth layer surrounding the first layer and a sixth layer surrounding the third layer, and wherein at least one of the layers comprises methyl cellulose.

39. The softgel capsule of claim 28 wherein the first and second sheets respectively further comprise a fifth layer surrounding the first layer and a sixth layer surrounding the third layer, and wherein at least one of the layers comprises ethyl cellulose.

40. The softgel capsule of claim 29 wherein the first and second sheets respectively further comprise a fifth layer surrounding the first layer and a sixth layer surrounding the third layer, and wherein at least one of the layers comprises hydroxypropylmethyl cellulose.

41. A softgel having two opposing ends divided at a seam having at least one sheet covering each end, the at least one sheet comprising at least two stacked layers of substantially uniform thickness, wherein at least one of the two stacked layers comprises cellulose acetate phthalate.

42. A softgel having two opposing ends divided at a seam having at least one sheet covering each end, the at least one sheet comprising at least two stacked layers of substantially uniform thickness, wherein at least one of the two stacked layers comprises methyl cellulose.

43. A softgel having two opposing ends divided at a seam having at least one sheet covering each end, the at least one sheet comprising at least two stacked layers of substantially uniform thickness, wherein at least one of the two stacked layers comprises ethyl cellulose.

44. A softgel having two opposing ends divided at a seam having at least one sheet covering each end, the at least one sheet comprising at least two stacked layers of substantially uniform thickness, wherein at least one of the two stacked layers comprises hydroxypropylmethyl cellulose.

45. The softgel capsule of claim 26 wherein the second and fourth layers comprise cellulose acetate phthalate.

Assignments (10)
RELEASE (REEL 032403 / FRAME 0790) Recorded Sep 28, 2017
From: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
To: BANNER PHARMACAPS INC.
Reel/Frame 044038/0028 →
NOTICE OF SUCCESSION OF AGENCY FOR PATENT SECURITY INTEREST PREVIOUSLY RECORDED AT REEL/FRAME (032403/0790) Recorded Jul 12, 2017
From: UBS AG, STAMFORD BRANCH, AS PRIOR AGENT
To: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH, AS SUCCESSOR AGENT
Reel/Frame 043173/0005 →
NUNC PRO TUNC ASSIGNMENT Recorded Jun 29, 2017
From: BANNER LIFE SCIENCES LLC
To: PATHEON SOFTGELS INC
Reel/Frame 043032/0619 →
RELEASE OF SECURITY INTEREST Recorded Jul 31, 2015
From: UBS AG, STAMFORD BRANCH
To: BANNER LIFE SCIENCES LLC; BANNER PHARMACAPS INC.
Reel/Frame 036224/0623 →
RELEASE OF SECURITY INTEREST Recorded Jul 31, 2015
From: UBS AG, STAMFORD BRANCH
To: BANNER LIFE SCIENCES LLC
Reel/Frame 036239/0188 →
SECURITY INTEREST Recorded Mar 5, 2015
From: BANNER LIFE SCIENCES LLC
To: UBS AG, STAMFORD BRANCH, AS COLLATERAL AGENT
Reel/Frame 035133/0328 →
NUNC PRO TUNC ASSIGNMENT Recorded Nov 19, 2014
From: BANNER PHARMACAPS INC
To: BANNER LIFE SCIENCES LLC
Reel/Frame 034294/0916 →
TERMINATION AND RELEASE OF SECURITY INTEREST IN PATENT RIGHTS Recorded Apr 23, 2014
From: MORGAN STANLEY SENIOR FUNDING, INC.
To: BANNER PHARMACAPS INC.
Reel/Frame 032745/0454 →
SECURITY INTEREST Recorded Mar 11, 2014
From: BANNER PHARMACAPS INC.
To: UBS AG, STAMFORD BRANCH, AS COLLATERAL AGENT
Reel/Frame 032403/0790 →
SECURITY AGREEMENT Recorded Dec 17, 2012
From: BANNER PHARMACAPS INC.
To: MORGAN STANLEY SENIOR FUNDING INC., AS COLLATERAL AGENT
Reel/Frame 029481/0962 →