Spacer or actuator for inertial removal of the non-respirable fraction of medicinal aerosols
View Patent ↗The invention comprises a medicinal inhaler spacer or actuator comprising a chamber having a proximal end closed by a proximal plate, a tangentially aligned inlet on the proximal end of the chamber, a tapered distal end, and an outlet extending through the proximal plate into and communicating with the chamber. Spacers of the present invention may be used to increase the respirable fraction of a medicinal aerosol inhaler. The invention also comprises medicinal aerosol inhalers and methods of delivering drug to the lung of a mammal employing these spacers.
1. A medicinal aerosol inhaler comprising:
an aerosol generation system;
a medicinal inhaler spacer wherein a chamber having a proximal end is closed by a proximal plate, a tangentially aligned inlet on the proximal end of the chamber, a tapered distal end, and an outlet extending through the proximal plate into and communicating with the chamber; and
a mouthpiece,
wherein the inlet of the spacer is in fluid communication with the aerosol generation system and the outlet of the spacer is in fluid communication with the mouthpiece,
wherein the aerosol produced by the aerosol generation system passes through the inlet and into the chamber.
2. A medicinal aerosol inhaler comprising:
an aerosol generation system;
a medicinal inhaler spacer wherein a chamber having a proximal end is closed by a proximal plate, a tangentially aligned inlet on the proximal end of the chamber, a tapered distal end, and an outlet extending through the proximal plate into and communicating with the chamber, wherein the chamber has only one inlet and one outlet; and
a mouthpiece,
wherein the inlet of the spacer is in fluid communication with the aerosol generation system and the outlet of the spacer is in fluid communication with the mouthpiece,
wherein the aerosol produced by the aerosol generation system passes through the inlet and into the chamber.