IP Library Granted Patent US 7,186,796
Granted Patent B2
US 7,186,796 · App. 10/373,542 · Granted Mar 6, 2007

Method for drying water-borne materials

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Quick Facts
Patent No.
US 7,186,796
App. No.
10/373,542
Granted
Mar 6, 2007
Kind
B2
Abstract

Provided is a method of isolating a bio-molecule from a water-borne mixture, the method comprising: contacting the water-borne mixture with dimethyl ether to form solid particles of the bio-molecule.

Claims (34)

1. A method of isolating a bio-molecule from a water-borne mixture, the method comprising: removing an aqueous solvent from the water-borne mixture by contacting the water-borne mixture with dimethyl ether to form solid particles of the bio-molecule.

2. The method as recited in claim 1 , wherein the water-borne mixture comprises the bio-molecule and a solvent component.

3. The method as recited in claim 1 , wherein the water-borne mixture is a suspension.

4. The method as recited in claim 1 , wherein the contacting is conducted at a temperature of 0 to 250° C. and the dimethyl ether is at a pressure range from P c to 10×P c , wherein P c is the critical pressure of dimethyl ether.

5. The method of claim 4 , wherein the contacting is conducted at a temperature of 0 to 80° C. and the dimethyl ether is at a pressure range from P c to 2×P c .

6. The method as recited in claim 1 , wherein the contacting is conducted at a temperature of 0 to 126.5° C. and the dimethyl ether is at a pressure range from 100 psi to 2×P c , wherein P c is the critical pressure of dimethyl ether.

7. The method as recited in claim 6 wherein the contacting is conducted at a temperature of 0 to 60° C. and the dimethyl ether is at a pressure range from 200 psi to P c .

8. The method as recited in claim 1 , wherein the contacting is conducted at a temperature of 0 to 126.5° C. and the dimethyl ether is at a pressure range from 50 psi to P c , wherein P c is the critical pressure of dimethyl ether.

9. The method as recited in claim 8 wherein the contacting is conducted at a temperature of 0 to 60° C.

10. The method as recited in claim 1 , wherein the dimethyl ether is introduced into a pressurized chamber containing the water-borne mixture.

11. The method as recited in claim 1 , wherein the water-borne mixture is injected into a stream of the dimethyl ether.

12. The method as recited in claim 1 , wherein the bio-molecule is a protein.

13. The method as recited in claim 12 , wherein the protein is a hormone.

14. The method as recited in claim 13 , wherein the hormone is insulin.

15. The method as recited in claim 12 , wherein the protein is an enzyme.

16. The method as recited in claim 1 , wherein the bio-molecule is a polynucleotide.

17. The method as recited in claim 16 , wherein the polynucleotide is DNA.

18. A method of isolating a material from a water borne mixture, the method comprising: removing an aqueous solvent from the water-borne mixture by contacting the water borne mixture with dimethyl ether to form dry particle of the material.

19. The method as recited in claim 18 , wherein the material is an organic substance.

20. The method as recited in claim 18 , wherein the material is an inorganic substance.

21. The method as recited in clam 18 , wherein the material in an edible or potable foodstuff.

22. The method as recited in claim 18 , wherein the water-borne mixture comprises the material and a solvent component.

23. The method as recited in claim 18 , wherein the material is silica gel.

24. The method as recited in claim 18 , wherein the material is a pharmaceutical.

25. The method as recited in claim 18 , wherein the water-borne mixture is a suspension.

26. The method as recited in claim 18 , wherein the water-borne mixture is an emulsion.

27. The method as recited in claim 18 , wherein the water-borne mixture is a micro-emulsion.

28. The method as recited in claim 18 , wherein the water-borne mixture comprises liposome suspended in aqueous media.

29. The method as recited in claim 18 , wherein the water-borne mixture is an aqueous solution.

30. The method as recited in claim 18 , wherein the contact is conducted at a temperature of 0 to 250° C. and the dimethyl ether is at a pressure range of 50 psi to 10×P c , wherein P c is the critical pressure of dimethyl ether.

31. The method as recited in claim 18 , wherein the contact is conducted at a temperature of 0 to 126.5° C. and the dimethyl ether is at a pressure range of 50 psi to 2×P c , wherein P c is the critical pressure of dimethyl ether.

32. The method as recited in claim 18 , wherein the dimethyl ether is introduced into a pressurized chamber containing the water-borne mixture.

33. The method as recited in claim 18 , wherein the water-borne mixture is injected into a stream of dimethyl ether.

34. A method of purifying a desired substance contaminated with impurities contained in a water-borne mixture, the method comprising contacting the water-borne mixture with dimethyl ether to remove an aqueous solvent and the impurities from the desired substance.

Assignments (5)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 28, 2016
From: LAVIPHARM LABORATORIES, INC.
To: THALLIUM HOLDING COMPANY, LLC
Reel/Frame 037610/0699 →
ASSIGNMENT OF SECURITY INTEREST Recorded Jan 28, 2016
From: MEDICAL PROVIDER FINANCIAL CORPORATION, III
To: THALLIUM HOLDING COMPANY, LLC
Reel/Frame 037627/0778 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 21, 2014
From: THE PHASEX CORPORATION
To: GREEN RECOVERY TECHNOLOGIES LLC
Reel/Frame 032309/0202 →
SECURITY AGREEMENT Recorded Jan 23, 2006
From: LAVIPHARM LABORATORIES, INC.
To: MEDICAL PROVIDER FINANCIAL CORPORATION, III
Reel/Frame 017050/0835 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 1, 2003
From: KRUKONIS, VAL; WILLIAMS, KARA T.; GUDINAS, ANTHONY; HANS, SHONEMANN; WETMORE, PAULA
To: PHASEX CORPORATION
Reel/Frame 014219/0871 →