IP Library › Granted Patent US 6,960,615
Granted Patent B2
US 6,960,615 · App. 10/375,492 · Granted Nov 1, 2005

Carbamide peroxide compositions for the treatment of dermatological disorders and methods for their use

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Quick Facts
Patent No.
US 6,960,615
App. No.
10/375,492
Granted
Nov 1, 2005
Kind
B2
Abstract

Topical compositions which include urea and carbamide peroxide are described. Compositions having a pH in the acidic range, particularly in the range of about 2.5 to about 9 are also described. Methods for treating dermatological disorders using the composition are also described.

Claims (11)

1. A topical composition suitable for the treatment of acne comprising:

a stable combination of a first component comprising about 0.1 to about 40 weight % of urea as an active agent and a second component comprising about 0.5 to about 30 weight % of carbamide peroxide as an active agent, the stable combination being safe and effective for the treatment of acne, wherein the topical composition is free from other active agents; and

a dermatologically acceptable carrier.

2. The composition of claim 1 wherein the composition has a pH of about 2.5 to about 9.

3. The composition of claim 1 , wherein the carbamide peroxide is present in an amount of about 4 to about 15% by weight.

4. The composition of claim 1 , wherein the carbamide peroxide is present in an amount of about 4.5 to about 9% by weight.

5. The composition of claim 1 , wherein the urea is present in an amount of about 5 to about 20% by weight.

6. The composition of claim 1 , wherein the carbamide peroxide is present in an amount of about 15% by weight and the urea is present in an amount of about 10% by weight.

7. The composition of claim 1 , wherein the composition is formulated as a cream.

8. The composition of claim 1 , wherein the composition is formulated as a gel.

9. The composition of claim 1 , wherein the composition is formulated as an ointment.

Assignments (9)
PATENT RELEASE Recorded Mar 20, 2015
From: ROYAL BANK OF CANADA, AS COLLATERAL AGENT
To: FOUGERA PHARMACEUTICALS INC. (F.K.A. NYCOMED US INC.)
Reel/Frame 035233/0381 →
PATENT SECURITY AGREEMENT Recorded Oct 21, 2011
From: FOUGERA PHARMACEUTICALS INC. (F.K.A. NYCOMED US INC.)
To: ROYAL BANK OF CANADA, AS COLLATERAL AGENT
Reel/Frame 027103/0716 →
CHANGE OF NAME Recorded Oct 5, 2011
From: NYCOMED US INC.
To: FOUGERA PHARMACEUTICALS INC.
Reel/Frame 027021/0146 →
MERGER Recorded Sep 15, 2008
From: BRADLEY PHARMACEUTICALS, INC.
To: NYCOMED US INC.
Reel/Frame 021561/0442 →
SECURITY AGREEMENT Recorded Feb 27, 2008
From: WACHOVIA BANK, NATIONAL ASSOCIATION
To: BRADLEY PHARMACEUTICALS, INC.
Reel/Frame 020566/0898 →
NOTICE OF GRANT OF SECURITY INTEREST Recorded Jan 30, 2008
From: BRADLEY PHARMACEUTICALS, INC.
To: WACHOVIA BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT
Reel/Frame 020431/0325 →
NOTICE OF GRANT OF SECURITY INTEREST Recorded Jan 3, 2006
From: BRADLEY PHARMACEUTICALS, INC.
To: WACHOVIA BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT
Reel/Frame 016976/0403 →
NOTICE OF GRANT OF SECURITY INTEREST Recorded Nov 15, 2004
From: BRADLEY PHARMACEUTICALS, INC.
To: WACHOVIA BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT
Reel/Frame 015355/0622 →
NOTICE OF GRANT OF SECURITY INTEREST Recorded Sep 28, 2004
From: BRADLEY PHARMACEUTICALS, INC.
To: WACHOVIA BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT
Reel/Frame 015190/0001 →