IP Library Granted Patent US 7,214,386
Granted Patent B2
US 7,214,386 · App. 10/384,750 · Granted May 8, 2007

Method for the treatment and prevention of overweight in mammals

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Quick Facts
Patent No.
US 7,214,386
App. No.
10/384,750
Granted
May 8, 2007
Kind
B2
Abstract

The present invention relates to a method for the prevention and/or treatment of overweight in mammals. More particularly the invention is concerned with such a method comprising the enteral administration to a mammal of a preparation comprising an effective amount of a combination of dill or an isolate thereof and one or more components capable of stimulating in vivo lipolysis. Suitable examples of components capable of stimulating in vivo lipolysis include methylxanthines, adrenergic amines, Paullinia cupana or an isolate thereof, Zingziber officinale or an isolate thereof, Camellia sinensis or an isolate thereof, Ilex paraguayiensis or an isolate thereof. Another aspect of the invention relates to a solid or semi-solid unit dosage, preferably selected from the group consisting of tablets, pills, microparticles, microspheres, suppositories, capsules, caplets and the like, that is suitable for enteral unitary administration to human subjects and other mammals comprising: a. dill or an isolate thereof in an amount equivalent to between 5 mg and 20 g dill and b. a component capable of stimulating in vivo lipolysis.

Claims (14)

1. A solid or semisolid unit dosage selected from the group consisting of tablets, pills, microparticles, microspheres, suppositories, capsules and caplets, that is suitable for enteral unitary administration to human subjects and other mammals comprising:

a. dill or an extract thereof in an amount equivalent to between 5 mg and 20 g dill;

b. between 10 and 4000 mg caffeine; and

c. between 5 mg and 20 g Camellia sinensis.

2. The unit dosage according to claim 1 , wherein the Camellia sinensis is in a daily dosage unit of 0.1 mg –100 mg per kg of body weight.

3. A solid or semi-solid unit dosage for enteral unitary administration to human subjects and other mammals comprising:

a. dill or an extract thereof in an amount equivalent to between 5 mg and 20 g dill;

b. between 10 and 4000 mg caffeine;

c. between 5 mg and 20 g Camellia sinensis ; and

d. a pharmaceutically acceptable carrier.

4. The unit dosage according to claim 3 wherein the Camellia sinensis is in a daily dosage unit of 0.1 mg–100 mg per kg of body weight.

5. A solid or semi-solid unit dosage comprising:

a combination of between 5 mg and 20 g dill or an extract thereof, between 10 and 4000 mg caffeine, and between 5 mg and 20 g Camellia sinensis in a unit form selected from the group consisting of tablets, pills, microparticles, microspheres, suppositories, capsules and caplets.

6. The unit dosage according to claim 5 wherein the Camellia sinensis is in a daily dosage unit of 0.1 mg–100 mg per kg of body weight.

Assignments (15)
RELEASE OF SECURITY INTEREST Recorded Jan 15, 2026
From: BANK OF CHINA LIMITED, MACAU BRANCH, AS SECURITY AGENT
To: GNC HOLDINGS, LLC; GNC INTERMEDIATE IP HOLDINGS, LLC; GNC INTELLECTUAL PROPERTY HOLDINGS, LLC
Reel/Frame 073484/0127 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 16, 2021
From: GENERAL NUTRITION INVESTMENT COMPANY
To: GNC HOLDINGS, LLC
Reel/Frame 055941/0553 →
RELEASE OF SECURITY INTEREST PREVIOUSLY RECORDED AT REEL/FRAME (045599/0344) Recorded Oct 12, 2020
From: JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT
To: GENERAL NUTRITION INVESTMENT COMPANY
Reel/Frame 054046/0667 →
RELEASE OF SECURITY INTEREST Recorded Oct 9, 2020
From: GLAS TRUST COMPANY LLC, AS COLLATERAL AGENT (AS SUCCESSOR TO JPMORGAN CHASE BANK, N.A.)
To: GNC CORPORATION; GENERAL NUTRITION CENTERS, INC.; GENERAL NUTRITION CORPORATION; GNC TRANSPORTATION, LLC; GNC FUNDING, INC.; GENERAL NUTRITION INVESTMENT COMPANY
Reel/Frame 054015/0001 →
SECURITY INTEREST Recorded Oct 9, 2020
From: GENERAL NUTRITION INVESTMENT COMPANY; GNC HOLDINGS, LLC; GNC INTERMEDIATE IP HOLDINGS, LLC; GNC INTELLECTUAL PROPERTY HOLDINGS, LLC
To: GLAS TRUST COMPANY LLC, AS COLLATERAL AGENT
Reel/Frame 054034/0453 →
SECURITY INTEREST Recorded Oct 8, 2020
From: GNC HOLDINGS, LLC
To: BANK OF CHINA LIMITED, MACAU BRANCH, AS SECURITY AGENT
Reel/Frame 054025/0001 →
ASSIGNMENT OF SECURITY INTEREST IN PATENTS PREVIOUSLY RECORDED AT REEL/FRAME (025958/0631) Recorded Jun 1, 2020
From: JPMORGAN CHASE BANK, N.A.
To: GLAS TRUST COMPANY LLC
Reel/Frame 052804/0979 →
PATENT SECURITY AGREEMENT Recorded Mar 14, 2018
From: GENERAL NUTRITION INVESTMENT COMPANY
To: JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT
Reel/Frame 045599/0344 →
SECURITY AGREEMENT Recorded Mar 15, 2011
From: GNC CORPORATION; GENERAL NUTRITION CENTERS, INC.; GENERAL NUTRITION CORPORATION; GENERAL NUTRITION INVESTMENT COMPANY; GNC TRANSPORTATION, LLC; GNC FUNDING, INC.
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 025958/0631 →
RELEASE OF SECURITY INTEREST Recorded Mar 4, 2011
From: JPMORGAN CHASE BANK, N.A.
To: GENERAL NUTRITION INVESTMENT COMPANY
Reel/Frame 025905/0054 →
SECURITY AGREEMENT Recorded Jun 10, 2009
From: GENERAL NUTRITION INVESTMENT COMPANY
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 022804/0237 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 15, 2007
From: N.V. NUTRICIA
To: GENERAL NUTRITION INVESTMENT COMPANY
Reel/Frame 019955/0955 →
RELEASE OF SECURITY INTEREST AT REEL/FRAME NO. 14934/0916 Recorded Apr 9, 2007
From: LEHMAN COMMERCIAL PAPER, INC.
To: GENERAL NUTRITION CORPORATION
Reel/Frame 019134/0223 →
SECURITY AGREEMENT Recorded Dec 30, 2003
From: GENERAL NUTRITION CORPORATION
To: LEHMAN COMMERCIAL PAPER INC., AS ADMINISTRATIVE AGENT
Reel/Frame 014934/0916 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 13, 2003
From: RAGGERS, RENE JOHN; VERLAAN, GEORGE
To: N.V. NUTRICIA
Reel/Frame 013733/0349 →