IP Library Granted Patent US 6,908,436
Granted Patent B2
US 6,908,436 · App. 10/385,580 · Granted Jun 21, 2005

Method of measuring endothelial function in a person

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Quick Facts
Patent No.
US 6,908,436
App. No.
10/385,580
Granted
Jun 21, 2005
Kind
B2
Abstract

A method of measuring endothelial function in a person ( 2 ), which method comprises applying pressure to one arm of the person ( 2 ) such as to restrict blood flow in the arm ( 6 ), releasing the pressure in order to cause an increase in blood flow in the arm ( 6 ) due to reactive hyperaemia, and then measuring the difference in pulse propagation time between the two arms ( 6, 8 ) of the person.

Claims (7)

1. A method of measuring endothelial function in a person, which method comprises applying pressure to one arm of the person such as to restrict blood flow in the arm, releasing the pressure in order to cause an increase in blood flow in the arm due to reactive hyperaemia, and then measuring the difference in pulse propagation time between the two arms of the person.

2. A method according to claim 1 in which the pressure is applied to the arm using restrictor means.

3. A method according to claim 2 in which the restrictor means is an inflatable restrictor means.

4. A method according to claim 3 in which the inflatable restrictor means is a blood pressure cuff.

5. A method according to claim 1 in which the difference in pulse propagation time is measured using photoplethysmography.

6. A method according to claim 5 in which the photoplethysmography comprises measuring the transmission/absorption of infra red light through/in the finger pulp of the person.

7. A method according to claim 1 in which the difference in the pulse propagation time between the two arms of the person is taken as a direct and continuous measure of the endothelial function.

Assignments (3)
CHANGE OF NAME Recorded May 10, 2010
From: CARDINAL HEALTH U.K. 232 LIMITED
To: CAREFUSION U.K. 232 LIMITED
Reel/Frame 024351/0982 →
CHANGE OF NAME Recorded Mar 13, 2009
From: MICRO MEDICAL LTD
To: CARDINAL HEALTH U.K. 232 LIMITED
Reel/Frame 022390/0835 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 20, 2004
From: CHOWIENCZYK, PHILIP JAN; LAWSON, CHRISTOPHER PATRICK; MILLASSEAU, SANDRINE CELINE
To: MICRO MEDICAL LTD
Reel/Frame 015269/0578 →