Control solution for photometric analysis
View Patent ↗An aqueous control solution is disclosed for use with a spectrophotometer or photometric test strip that includes a predetermined amount of an analyte, a hydrophobic reference dye and a surfactant. In one embodiment, the aqueous control solution is applied to a photometric test strip having a chemical that oxidizes glucose and consequently forms hydrogen peroxide which reacts with an indicator dye that is also present on the strip. In this embodiment, the control solution includes a predetermined amount of glucose, an infrared reference dye, sodium dodecyl sulfate, and the indicator dye, such as sulforhodamine B.
1. An aqueous control solution, comprising a predetermined amount of glucose, C 62 H 96 N 6 SbF 6 , sodium dodecyl sulfate, and an indicator dye selected from the group consisting of sulforhodamine B and rose bengal.
2. The solution of claim 1 , further comprising a preservative.
3. The solution of claim 2 , wherein the preservative is selected from the group consisting of diazolidinyl urea, sodium benzoate, potassium benzoate, benzalkonium chloride, chlorhexidine, imidazolidinyl urea, 5-chloro-2-methyl-4-isothiazolinone, 2-methyl-4-isothiazoline-3-one and mixtures thereof.
4. The solution of claim 3 , wherein the preservative is diazolidinyl urea or a mixture of 5-chloro-2-methyl-4-isothiazolin-one and 2-methyl-4-isothiazoline-3-one.
5. The solution of claim 1 , further comprising a buffer.
6. The solution of claim 5 , wherein the buffer is selected from the group consisting of a citrate buffer, an imidazole buffer and a N-2-hydroxyethyl piperazine-N-2-ethanesulfonic acid buffer.
7. The solution of claim 1 , further comprising a viscosity enhancer.
8. The solution of claim 7 , wherein the viscosity enhancer is glycerol, polyvinylpyrrolidone or a combination thereof.
9. The solution of claim 1 , further comprising:
a) a citrate buffer or a N-2-hydroxyethyl piperazine-N-2-ethanesulfonic acid buffer;
b) glycerol, polyvinylpyrrolidone, or a combination thereof; and
c) diazolidinyl urea, or a combination of 5-chloro-2-methyl4-isothiazolin-one and 2-methyl-4-isothiazoline-3-one.