IP Library Granted Patent US 7,283,253
Granted Patent B2
US 7,283,253 · App. 10/389,269 · Granted Oct 16, 2007

Multi-axis integration system and method

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Quick Facts
Patent No.
US 7,283,253
App. No.
10/389,269
Granted
Oct 16, 2007
Kind
B2
Abstract

An image acquisition system and method employing multi-axis integration (MAI) may incorporate both optical axis integration (OAI) and time-delay integration (TDI) techniques. Disclosed MAI systems and methods may integrate image data in the z direction as the data are acquired, projecting the image data prior to deconvolution. Lateral translation of the image plane during the scan in the z direction may allow large areas to be imaged in a single scan sequence.

Claims (29)

1. A method of acquiring data; said method comprising:

scanning an object along an optical axis;

simultaneously scanning said object along a lateral axis;

acquiring image data of said object during said scanning and said simultaneously scanning; and

integrating said image data concomitantly with said acquiring.

2. The method of claim 1 wherein said scanning comprises providing relative translation along said optical axis of said object and an image plane.

3. The method of claim 1 wherein said simultaneously scanning comprises providing relative translation along said lateral axis of said object and an image plane.

4. The method of claim 1 wherein said acquiring comprises utilizing a charge-coupled device.

5. The method of claim 1 wherein said integrating comprises utilizing an image processor.

6. The method of claim 1 further comprising deblurring said image data subsequent to said integrating.

7. The method of claim 1 further comprising deconvolving said image data subsequent to said integrating.

8. The method of claim 7 further comprising calculating a two-dimensional projection of said object from a projection of said image data and a projection of an optical point-spread-function.

9. The method of claim 2 wherein said scanning further comprises selectively alternating a direction of said relative translation along said optical axis.

10. The method of claim 3 wherein said simultaneously scanning comprises synchronizing said relative translation along said lateral axis with a rate associated with said acquiring.

11. A method of acquiring image data of an object; said method comprising:

performing an optical axis integration scan;

simultaneously executing a time-delay integration scan sequence; and

selectively repeating said performing and said executing.

12. The method of claim 11 wherein said performing comprises acquiring image data of said object at an image plane positioned along an optical axis.

13. The method of claim 12 wherein said performing further comprises providing relative translation along said optical axis of said object and said image plane.

14. The method of claim 13 wherein said executing comprises providing relative translation along a lateral axis of said object and said image plane.

15. The method of claim 13 wherein said performing further comprises selectively alternating a direction of said relative translation along said optical axis.

16. The method of claim 14 wherein said executing comprises synchronizing said relative translation along said lateral axis with a data acquisition rate associated with an imaging device.

17. The method of claim 12 wherein said acquiring comprises utilizing a charge-coupled device.

18. The method of claim 12 wherein said performing further comprises integrating said image data concomitantly with said acquiring.

19. The method of claim 18 wherein said integrating comprises utilizing an image processor.

20. The method of claim 18 further comprising deblurring said image data subsequent to said integrating.

21. The method of claim 18 further comprising deconvolving said image data subsequent to said integrating.

22. The method of claim 21 further comprising calculating a two-dimensional projection of said object from a projection of said image data and a projection of an optical point-spread-function.

Assignments (5)
MERGER Recorded Apr 3, 2014
From: APPLIED PRECISION, INC.
To: GE HEALTHCARE BIO-SCIENCES CORP.
Reel/Frame 032595/0367 →
RELEASE OF SECURITY INTEREST Recorded Jun 3, 2011
From: SILICON VALLEY BANK
To: APPLIED PRECISION, INC.
Reel/Frame 026398/0420 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 11, 2008
From: APPLIED PRECISION, LLC
To: APPLIED PRECISION, INC.
Reel/Frame 021511/0562 →
SECURITY AGREEMENT Recorded Aug 4, 2008
From: APPLIED PRECISION, INC.
To: SILICON VALLEY BANK
Reel/Frame 021328/0695 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 13, 2003
From: REESE, STEVEN A.; BROWN, CARL S.; GOODWIN, PAUL C.
To: APPLIED PRECISION, LLC
Reel/Frame 014181/0339 →