IP Library › Granted Patent US 6,905,687
Granted Patent B2
US 6,905,687 · App. 10/394,058 · Granted Jun 14, 2005

Human procalcitonin and the preparation and use thereof

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Quick Facts
Patent No.
US 6,905,687
App. No.
10/394,058
Granted
Jun 14, 2005
Kind
B2
Abstract

The invention relates to human procalcitonin and the preparation and use thereof. In particular, a process for preparing human procalcitonin is described wherein a gene coding for a polypeptide comprising the amino acid sequence of human procalcitonin is inserted into a vector; a host organism is transformed with this gene-containing vector; and the polypeptide expressed by the host organism is isolated. Furthermore the use of the polypeptides according to the invention, in particular as medicaments and diagnostic agents is described.

Claims (16)

1. An isolated recombinant polypeptide comprising an amino acid sequence SEQ ID NO: 8.

2. An isolated recombinant polypeptide comprising an amino acid sequence SEQ ID NO: 9.

3. A composition comprising the polypeptide according to claim 1 and a pharmaceutically-acceptable, sterile injection medium.

4. A composition comprising the polypeptide according to claim 2 and a pharmaceutically-acceptable, sterile injection medium.

5. A diagnostic agent comprising the polypeptide according to claim 1 .

6. A diagnostic agent comprising the polypeptide according to claim 2 .

7. A composition comprising the polypeptide according to claim 1 and a pharmaceutically-acceptable carrier.

8. A composition comprising the polypeptide according to claim 2 and a pharmaceutically-acceptable carrier.

9. A method for preparing antibodies to the polypeptide according to claim 1 comprising immunizing a host with said polypeptide.

10. A method for preparing antibodies to the polypeptide according to claim 2 comprising immunizing a host with said polypeptide.

11. A standard and/or a control composition comprising the polypeptide according to claim 1 .

12. A standard and/or a control composition comprising the polypeptide according to claim 2 .

13. A test kit comprising the polypeptide according to claim 1 .

14. A test kit comprising the polypeptide according to claim 2 .

15. A solution comprising the polypeptide according to claim 1 , wherein said polypeptide is stable during liquid storage.

16. A solution comprising the polypeptide according to claim 2 , wherein said polypeptide is stable during liquid storage.

Assignments (1)
CHANGE OF NAME Recorded Feb 26, 2009
From: DADE BEHRING MARBURG GMBH
To: SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH
Reel/Frame 022309/0627 →