IP Library Granted Patent US 7,497,818
Granted Patent B2
US 7,497,818 · App. 10/397,940 · Granted Mar 3, 2009

Delivery system and method for interstitial radiation therapy

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Quick Facts
Patent No.
US 7,497,818
App. No.
10/397,940
Granted
Mar 3, 2009
Kind
B2
Abstract

A delivery system and method for interstitial radiation therapy comprising a substantially axially stiff and longitudinally flexible elongated member made of material, which is bio-absorbable in living tissue and a plurality of radioactive seeds dispersed in a predetermined array within the member. The delivery system and method further customize the member based on a prescription.

Claims (50)

1. A prescription method of treating tissue comprising the steps of:

first creating a prescription tissue treatment plan for the tissue to be treated, said prescription treatment plan specifying a number and a spacing of a plurality of treatment seeds to be provided in a treatment strand, the spacing of said plurality of treatment seeds unrestricted by any use of spacers and independently set by prescription and according to the treatment plan, the spacing set independently of any structure of a mold for the treatment strand; and

second creating the treatment strand by molding said plurality of treatment seeds in a material.

2. The method of claim 1 wherein:

said first creating step is performed by a person treating a patient; and

said second creating step is performed by an entity that fills prescriptions by forming the treatment strand, which entity fills prescriptions from a plurality of patients.

3. The method of claim 1 wherein:

said first creating step further comprises specifying that the plurality of treatments seeds is a plurality of radioactive seeds and specifying a plurality of optimal spacings between each pair of seeds; and

said second creating step creates a plurality of treatment strands to the specified optimal spacings prescribed by the treatment plan.

4. The method of claim 3 wherein:

said second creating step further comprises positioning the plurality of radioactive seeds in a mold at the optimal spacings and dispensing the material to mold the plurality of radioactive seeds in the plurality of optimal spacings.

5. The method of claim 4 wherein: the dispensing step further comprises using said material that is a bio-absorbable material.

6. The method of claim 5 wherein: the dispensing step further comprises using said material that is a polymer material.

7. The method of claim 1 wherein:

said first creating step further comprises using imaging devices for creating the prescription treatment plan.

8. The method of claim 1 including:

receiving at least one of said plurality of treatment strands and implanting said treatment strand adjacent to the tissue to be treated.

9. The method of claim 1 including the step of using heated treatment seeds.

10. A prescription method of treating tissue comprising the steps of:

first accepting a prescription tissue treatment plan for the tissue to be treated, said prescription tissue treatment plan specifying the spacing of a plurality of treatment seeds to be provided in a treatment strand, the spacing of said plurality of treatment seeds being set by prescription according to the prescription tissue treatment plan and not by a mold; and

second, creating at least one said treatment strand by molding said plurality of treatment seeds in a material such that the spacing between said plurality of treatment seeds is specified by said treatment plan and not by a mold.

11. The method of claim 10 wherein said creating step creates said treatment strand by molding said plurality of treatment seeds in the polymer material.

12. The method of claim 10 further comprising specifying in said prescription tissue treatment plan a type of said treatment seed.

13. The method of claim 10 wherein said creating step further comprises generating said treatment strand to an optimal spacing prescribed in the prescription tissue treatment plan.

14. The method of claim 10 wherein said accepting step further comprises accepting said treatment plan created using an imaging device to image the tissue for which the prescription tissue treatment plan is prescribed.

15. The method of claim 10 wherein the first accepting step further comprises accepting the prescription tissue treatment plan wherein said prescription tissue treatment plan is created by a computer program.

16. A prescription method of treating tissue comprising the steps of:

first creating a prescription tissue treatment plan for the tissue to be treated;

specifying a number and a spacing of a plurality of treatment seeds to be provided in a treatment strand, said specifying the number and spacing step being according to the prescription tissue treatment plan and excluding use of spacers and restriction of any structure of a mold; and

forming the treatment strand by molding the plurality of treatment seeds in a material according to the prescription tissue treatment plan and excluding use of spacers and restriction of any structure of a mold.

17. A prescription method of treating tissue comprising the steps of:

first accepting a prescription tissue treatment plan for the tissue to be treated, said prescription tissue treatment plan specifying number and a spacing of a plurality of treatment seeds to be provided in a treatment strand, the spacing of said plurality of treatment seeds defined by the treatment plan and not by a structure of a mold; and

second creating the treatment strand by molding the plurality of treatment seeds in a material in accordance with the treatment plan.

18. The method of claim 17 wherein:

said first accepting step further comprises accepting the prescription tissue treatment plan wherein said prescription tissue treatment plan is created by a computer program.

19. The method of claim 17 wherein:

said first accepting step further comprises accepting the treatment plan wherein the prescription tissue treatment plan specifies using a plurality of radioactive seeds and optimal spacings between each pair of said plurality of radioactive seeds; and

said second creating step further comprises creating a plurality of said treatment strands to the specified optimal spacings prescribed.

20. A prescription method of treating tissue comprising the steps of:

first creating a prescription tissue treatment plan for the tissue to be treated, said prescription tissue treatment plan specifying a number and a spacing of a plurality of treatment seeds to be provided in a treatment strand, the spacing being independent of any structure of a mold; and

second creating the treatment strand by positioning said plurality of treatment seeds in a mold in accordance with the treatment plan and introducing a polymer material into the mold to thereby mold the seeds in the polymer material.

21. A prescription method of treating tissue comprising the steps of:

first accepting a prescription tissue treatment plan for the tissue to be treated, said prescription tissue treatment plan specifying a number and a spacing of a plurality of treatment seeds to be provided in a treatment strand, said spacing according to the prescription tissue treatment plan and being independently set without spacers and without any structural restrictions of a mold; and

second creating the treatment strand by positioning said plurality of treatment seeds in a mold in accordance with the treatment plan and introducing a polymer material into the mold to thereby mold the seeds in a the polymer material.

22. The method of claim 21 wherein:

said first accepting step further comprises accepting the tissue treatment plan wherein the tissue treatment plan is created by a computer program.

23. The method of claim 21 wherein:

said first accepting step further comprises accepting the prescription tissue treatment plan wherein the prescription tissue treatment plan specifies using a plurality of radioactive seeds and a plurality of optimal spacings between each pair of said plurality of radioactive seeds; and

said second creating step further comprises generating at least one treatment said strand to the plurality of optimal spacings.

24. A prescription treatment strand made in accordance with the process of claim 1 .

Assignments (8)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 13, 2016
From: ECKERT & ZIEGLER BEBIG S.A.
To: THERAGENICS CORPORATION
Reel/Frame 037475/0823 →
CORRECTIVE ASSIGNMENT TO CORRECT THE THE TOTAL ATTACHMENTS TO INCLUDE SCHEDULE A. DOCUMENT ID# 502678702. PREVIOUSLY RECORDED ON REEL 032145 FRAME 0713. ASSIGNOR(S) HEREBY CONFIRMS THE PATENT ASSIGNMENT AGREEMENT.. Recorded Feb 12, 2014
From: BIOCOMPATIBLES UK, LTD.
To: ECKERT & ZIEGLER BEBIG S.A.
Reel/Frame 032435/0086 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 5, 2014
From: BIOCOMPATIBLES UK, LTD.
To: ECKERT & ZIEGLER BEBIG S.A.
Reel/Frame 032145/0713 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 17, 2009
From: WORLD WIDE MEDICAL OF FLORIDA, LLC
To: BIOCOMPATIBLES UK LIMITED
Reel/Frame 022960/0970 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 15, 2009
From: IDEAMATRIX, INC.
To: WORLD WIDE MEDICAL OF FLORIDA, LLC
Reel/Frame 022960/0112 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 8, 2008
From: WORLD WIDE MEDICAL TECHNOLOGIES, LLC
To: BIOCOMPATIBLES UK LIMITED
Reel/Frame 021354/0292 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 1, 2005
From: LAMOUREUX, GARY
To: WORLDWIDE MEDICAL TECHNOLOGIES, L.L.C.
Reel/Frame 017073/0913 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 31, 2003
From: TERWILLIGER, RICHARD A.
To: IDEAMATRIX, INC.
Reel/Frame 014227/0296 →