Chemical absorbent
View Patent ↗A chemical absorbent comprises a hydrated mixture of a major proportion of a pharmaceutically acceptable hydroxide of a Group II metal and a minor proportion of silica, the chemical absorbent being substantially free of Group I metal ions. The chemical absorbent is particularly useful in low flow or closed circuit anaesthesia, and is advantageous in that it does not react with volatile anaesthetic agents in such a way as to cause the build up of toxic substances within an anaesthetic breathing circuit.
1. A chemical absorbent consisting essentially of a hydrated mixture of a pharmaceutically acceptable hydroxide of a Group II metal at a level of between 65% and 95% by weight of the chemical absorbent, silica at a level of between 5% and 10% by weight of the chemical absorbent, and water, the chemical absorbent being substantially free of Group I metal ions.
2. A chemical absorbent as claimed in claim 1 , which contains less than 0.5% w/w of Group I metal hydroxides.
3. A chemical absorbent as claimed in claim 1 , wherein the pharmaceutically acceptable hydroxide is insoluble or only sparingly soluble in water.
4. A chemical absorbent as claimed in claim 1 , wherein the pharmaceutically acceptable hydroxide is calcium hydroxide.
5. A chemical absorbent as claimed in claim 1 , wherein the pharmaceutically acceptable hydroxide accounts for 75% to 79% by weight of the chemical absorbent.
6. A chemical absorbent as claimed in claim 1 , which contains between 10% and 20% by weight of water.
7. A chemical absorbent as claimed in claim 1 , which contains between 12% and 16% by weight of water.
8. A chemical absorbent as claimed in claim 1 , in which other components are present only in amounts of less than 1% w/w.
9. A chemical absorbent as claimed in claim 1 , which consists solely of the hydroxide of a Group II metal, silica, water, and one or more pH-sensitive dyes and/or other pigments, the dyes and/or pigments accounting for less than 1% w/w of the composition.
10. A chemical absorbent as claimed in claim 1 , wherein the silica is a precipitated synthetic silica.
11. A chemical absorbent as claimed in claim 1 , which further comprises a pH-sensitive dye.
12. A chemical absorbent as claimed in claim 11 , wherein the pH-sensitive dye is present at a level of 0.001% to 0.1% by weight.
13. A chemical absorbent as claimed in claim 1 , which further comprises a pigment.
14. A chemical absorbent as claimed in claim 1 , which is in the form of granules.
15. A chemical absorbent as claimed in claim 14 , wherein the granules are cylindrical, spherical or substantially spherical.
16. A process for the manufacture of a chemical absorbent as claimed in claim 1 , which process comprises the steps of
a) mixing the pharmaceutically acceptable hydroxide and the silica,
b) adding water to form a paste, and
c) extruding or moulding the paste to form granules.
17. A process as claimed in claim 16 , further comprising drying the granules.
18. A process as claimed in claim 17 , wherein the granules are dried to a lower than desired water content and then rehydrated to a desired final water level.