IP Library Granted Patent US 7,597,847
Granted Patent B2
US 7,597,847 · App. 10/403,266 · Granted Oct 6, 2009

Analyzer having a stationary multifunction probe

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Quick Facts
Patent No.
US 7,597,847
App. No.
10/403,266
Granted
Oct 6, 2009
Kind
B2
Abstract

An analyzer, preferably a desktop analyzer, includes: a stationary probe capable of dispensing or aspirating a liquid; one or more of a movable test element or movable liquid source; and a conveyor for moving the movable test element or liquid source with respect to the stationary probe. In a preferred embodiment, the conveyor includes a dual rotor conveyor. A method of dispensing or aspirating a liquid into a test element includes: providing a movable test element having identifying marks, such as a barcode, thereon and a movable sample liquid supply; providing a stationary probe; reading the identifying marks to determine which test is to be performed and the dimensions of the test element; moving the movable sample liquid supply into registration with the probe; aspirating sample into the stationary probe; and moving the movable test element into registration with the probe, wherein the registration of the test element with the probe is controlled by the test to be performed. In a preferred embodiment, the method is implemented by a computer program interfacing with a computer.

Claims (34)

1. An analyzer comprising:

a stationary probe movable only along a single axis capable of dispensing or aspirating a liquid; and

a first reagent rotor for holding and moving with respect to the stationary probe a test element and at least one of a movable liquid supply and a probe tip dispenser;

a second incubator rotor arranged concentrically within the first rotor and adapted to receive the test element from the first rotor and to incubate a sample disposed in the second rotor; and

a waste collection container located on the first rotor.

2. An analyzer as claimed in claim 1 , wherein the probe comprises an aspirating and/or dispensing nozzle.

3. An analyzer as claimed in claim 1 , further comprising:

the movable liquid supply; and

a test element holder.

4. An analyzer as claimed in claim 3 , wherein the test element holder is located within the movable liquid supply.

5. An analyzer as claimed in claim 4 , wherein the movable liquid supply comprises a liquid supply section and a probe tip holder.

6. An analyzer as claimed in claim 3 , wherein the test element holder comprises a plurality of test holders.

7. An analyzer as claimed in claim 6 , wherein at least one of the test element holders contains different test elements than the test elements of other test element holders.

8. An analyzer as claimed in claim 7 , wherein the different test elements are potentiometric test elements and the test elements of the other test element holders are colorimetric test elements.

9. An analyzer as claimed in claim 4 , wherein the movable liquid supply further comprises a recess for the test element holder.

10. An analyzer as claimed in claim 1 , wherein the liquid comprises one or more of a liquid sample, a liquid reagent or a wash liquid.

11. An analyzer as claimed in claim 10 , further comprising a liquid reagent source and a liquid sample source, and optionally a wash liquid source.

12. An analyzer as claimed in claim 1 , further comprising an additional probe.

13. An analyzer as claimed in claim 1 , wherein the additional probe is a dispensing nozzle for dispensing a reference liquid for a potentiometric analysis.

14. An analyzer as claimed in claim 1 , further comprising a test element holder that comprises:

a body portion for holding the movable test element; and

a guide adapted to receive a probe to position the probe in a desired registration with a test element.

15. An analyzer as claimed in claim 14 , wherein the test holder further comprises a cover disposed over at least a portion of the body portion and test element and the guide comprises at least one opening in said cover.

16. An automated analyzer as claimed in claim 5 , wherein the liquid supply section includes a recess and the probe tip holder includes a recess.

17. An automated analyzer as claimed in claim 5 , wherein the liquid supply section and probe tip holder are integral.

18. An automated analyzer as claimed in claim 5 , wherein the movable liquid supply further comprises a recess for the test element holder.

19. An automated analyzer as claimed in claim 16 , wherein the liquid movable liquid supply further comprises a recess for the test element holder.

20. An automated analyzer as claimed in claim 19 , wherein the recess is disposed between the liquid supply section and the probe tip holder.

21. An analyzer according to claim 1 , wherein the analyzer is a desktop analyzer.

22. A desktop analyzer comprising:

a first rotor for holding a test element, and at least one of a sample reservoir for a sample to be analyzed, a wash reservoir, and a probe tip dispenser;

an incubator located on a second rotor arranged concentrically within the first rotor and adapted to receive the test element from the first rotor and to incubate a sample disposed in the second rotor;

a measurement device arranged to analyze a sample located in the second rotor; and

a waste collection container located on the first rotor.

Assignments (4)
RELEASE (REEL 060220 / FRAME 0711) Recorded Aug 22, 2025
From: BANK OF AMERICA, N.A.
To: QUIDEL CORPORATION; BIOHELIX CORPORATION; DIAGNOSTIC HYBRIDS, INC.; QUIDEL CARDIOVASCULAR INC.; ORTHO-CLINICAL DIAGNOSTICS, INC.; CRIMSON U.S. ASSETS LLC; CRIMSON INTERNATIONAL ASSETS LLC; MICRO TYPING SYSTEMS, INC.
Reel/Frame 072577/0536 →
RELEASE OF SECURITY INTEREST Recorded May 31, 2022
From: BANK OF AMERICA, N.A.
To: ORTHO-CLINICAL DIAGNOSTICS, INC.; CRIMSON U.S. ASSETS LLC; CRIMSON INTERNATIONAL ASSETS LLC
Reel/Frame 060219/0571 →
SECURITY AGREEMENT Recorded May 31, 2022
From: QUIDEL CORPORATION; BIOHELIX CORPORATION; DIAGNOSTIC HYBRIDS, INC.; QUIDEL CARDIOVASCULAR INC.; ORTHO-CLINICAL DIAGNOSTICS, INC.; CRIMSON U.S. ASSETS LLC; CRIMSON INTERNATIONAL ASSETS LLC; MICRO TYPING SYSTEMS, INC.
To: BANK OF AMERICA, N.A.
Reel/Frame 060220/0711 →
SECURITY INTEREST Recorded Jul 3, 2014
From: ORTHO-CLINICAL DIAGNOSTICS, INC; CRIMSON U.S. ASSETS LLC; CRIMSON INTERNATIONAL ASSETS LLC
To: BARCLAYS BANK PLC, AS COLLATERAL AGENT
Reel/Frame 033276/0104 →