Methods for modulating phototoxicity
View Patent ↗The invention relates to methods for modulating photodamage via the use of collagen derived molecules which either enhance or inhibit damage caused by ultraviolet light.
1. A method for treating photodamage in a human subject in need thereof, comprising applying to skin of said subject an amount of a photodamage modulator sufficient to modulate photodamage caused by ultraviolet light wherein said modulators is proline, 4-hydroxyproline or an alkyl ester thereof.
2. The method of claim 1 , wherein said modulator inhibits photodamage.
3. The method of claim 1 , wherein said proline alkyl ester comprises an alkyl moiety of 1–24 carbon atoms.
4. The method of claim 3 , wherein said proline alkyl ester is L-proline-OCH 3 or 4-OH-L-Pro-OCH 3 .
5. The method of claim 1 , comprising applying said modulator in the form of a cream, lotion, shampoo, spray or patch.