Tissue fastener and methods for using same
View Patent ↗In one embodiment, a hook fastener has a plurality of hooks and a loop fastener has a plurality of loops to secure tissues sections to one another. At least one of these fasteners has a porous surface to allow tissue ingrowth to secure the fastener to the tissue. In another embodiment, only a single fastener is used, with a section of tissue being treated to engage and mate with the fastener. The disclosed tissue fastening systems can be used for a number of applications. One such example includes fastening tissue sections by wrapping a tissue fastener around the tissue and securing the fastener on itself. A suture may also be secured with the tissue fastener.
1. A tissue fastening system for coupling first and second tissue sections, the system comprising:
a hook fastener having a tissue contacting side for contacting the first tissue section and a fastening side, positioned opposite said hook fastener tissue contacting side, with a plurality of hooks;
a loop fastener having a tissue contacting side for contacting the second tissue section and a fastening side, positioned opposite said loop fastener tissue contacting side, with a plurality of loops;
a suture being free of knots for engaging the first and second tissue sections to maintain the first and second tissue sections in a predetermined relationship;
said plurality of hooks engaging said plurality of loops with a portion of said suture being held therebetween to sandwich and secure said suture relative to the first and second tissue; and
an anchoring member for securing at least one of the hook and loop fasteners to tissue,
wherein:
the hook and loop fasteners are at least partially made of a biodegradable material;
the plurality of hooks engage the plurality of loops to couple the first and second tissue sections;
at least one of the hook and loop fasteners has an anchoring hole for receiving the anchoring member to thereby secure the at least one of the hook and loop fasteners to tissue, the anchoring member being made of a biodegradable material and selected from the group consisting of a staple, a rivet, and a suture; and
at least a portion of one of the hook fastener tissue contacting portion and the loop fastener tissue contacting portion has a porous surface including a plurality of pores, each having a size of about 0.1 microns to 1000 microns, allowing soft tissue ingrowth to thereby secure the fastener to soft tissue.
2. The fastening system of claim 1 wherein at least a portion of the porous surface is a mesh structure having an array of substantially uniform spaces.
3. The fastening system of claim 1 wherein at least a portion of the hook fastener tissue contacting portion has a porous surface allowing tissue ingrowth to thereby secure the hook fastener to the first tissue section and at least a portion of the loop fastener tissue contact portion has a porous surface allowing tissue ingrowth to thereby secure the loop fastener to the second tissue section.
4. The fastening system of claim 1 wherein at least one of the hook and loop fasteners includes a therapeutic agent.
5. The fastening system of claim 1 , wherein the porous surface has a series of randomly oriented fibers forming a series of pores having a range of sizes.
6. The fastening system of claim 1 , wherein at least one of said hook fastener and loop fastener includes a therapeutic agent.
7. The fastening system of claim 6 wherein the therapeutic agent is selected from the group consisting of IGF (insulin-like growth factors), TGF (transforming growth factors), FGB (fibroblast growth factors), EGF (epidermal growth factors), BMP (bone morphogenic proteins), and PDGF (platelet-derived growth factors).