IP Library › Granted Patent US 7,323,193
Granted Patent B2
US 7,323,193 · App. 10/433,588 · Granted Jan 29, 2008

Method of making demineralized bone particles

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Quick Facts
Patent No.
US 7,323,193
App. No.
10/433,588
Granted
Jan 29, 2008
Kind
B2
Abstract

Demineralized bone particles are obtained by demineralizing whole bone and thereafter subdividing the demineralized bone to provide the demineralized bone particles.

Claims (10)

1. A method of making demineralized bone particles which comprises demineralizing whole bone and thereafter subdividing the demineralized bone into demineralized bone particles, wherein subdividing of the demineralized bone is carried out by applying pressure to the demineralized bone using a mechanical press, wherein the pressure is applied from about 1,000 to about 40,000 psi.

2. The method of claim 1 wherein the bone is subjected to pressing while unconstrained.

3. The method of claim 2 wherein the product of pressing is subjected to an additional pressing while constrained.

4. The method of claim 1 wherein the bone is subjected to pressing while constrained.

5. The method of claim 1 wherein the product of pressing is subjected to an additional subdividing operation.

6. A method of making demineralized bone particles which comprises demineralizing whole bone and thereafter subdividing the demineralized bone into demineralized bone particles, wherein subdividing of the demineralized bone is carried out by applying pressure to the demineralized bone using a mechanical press, wherein the pressure is applied from about 5,000 to about 20,000 psi.

7. The method of claim 6 wherein the bone is subjected to pressing while unconstrained.

8. The method of claim 7 wherein the product of pressing is subjected to an additional pressing while constrained.

9. The method of claim 6 wherein the bone is subjected to pressing while constrained.

10. The method of claim 6 wherein the product of pressing is subjected to an additional subdividing operation.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 28, 2011
From: OSTEOTECH, INC.
To: WARSAW ORTHOPEDIC, INC.
Reel/Frame 026196/0585 →