IP Library Granted Patent US 6,846,289
Granted Patent B2
US 6,846,289 · App. 10/455,878 · Granted Jan 25, 2005

Integrated x-ray and ultrasound medical imaging system

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Quick Facts
Patent No.
US 6,846,289
App. No.
10/455,878
Granted
Jan 25, 2005
Kind
B2
Abstract

An integrated x-ray and ultrasound medical imaging system is provided, wherein a radiation detection means and ultrasound transducer may be disposed for scanning movement for image acquisition along either the same or substantially coincidental paths. The radiation detection means and ultrasound transducer may be advantageously located on the same side of the imaged body portion. The x-ray and ultrasound imaging operations may be sequential, partially overlapping, or synchronous. By virtue of the noted arrangement, increased accuracy and medical efficiencies can be realized.

Claims (43)

1. An apparatus for use in generating images of a selected region of a patient's body, comprising:

a radiation source for transmitting a radiation signal through a selected region of a patient's body;

radiation detection means, positionable for scanning movement along a first path, for receiving a portion of said radiation signal passing through a selected region of a patient's body during said scanning movement and providing a first image signal responsive thereto; and

an ultrasound transducer, positionable for scanning movement along a second path, for receiving an ultrasound signal from a selected region of a patient's body during said second movement and providing a second image signal responsive thereto, wherein said second path is one of the same and substantially coincidental to said first path.

2. An apparatus as recited in claim 1 , wherein a selected region of a patient's body is positionable so that said radiation source is on a first side thereof and said radiation detection means and said ultrasound transducer are both positioned on an opposing, second side thereof.

3. An apparatus as recited in claim 2 , further comprising:

a support layer having a first side for contacting a selected region of a patient's body and an opposing second side, wherein said radiation detection means and said ultrasound transducer are both located adjacent to said second side of the supporting layer.

4. An apparatus as recited in claim 3 , wherein said first side of the support layer is of an arcuate configuration.

5. An apparatus as recited in claim 4 , wherein said first path is arcuate.

6. An apparatus as recited in claim 3 , wherein said first side of the support layer is of a planar configuration.

7. An apparatus as recited in claim 6 , wherein said second path is linear.

8. An apparatus as recited in claim 1 , further comprising:

processor means for controlling operation of said radiation source, radiation detection means and ultrasound transducer, wherein said radiation detection means and said ultrasound transducer are controllable for at least partially overlapping imaging operations.

9. An apparatus as recited in claim 8 , further comprising:

drive means for effecting co-scanning movement of said radiation detection means and said ultrasound transducer.

10. An apparatus as recited in claim 9 , wherein said radiation detection means and said ultrasound transducer are interconnected in fixed relation to one another.

11. An apparatus as recited in claims 10 , wherein one of said radiation detection means and said ultrasound transducer is supportably carried by the other.

12. An apparatus as recited in claim 1 , wherein said radiation detection means is maintained at a substantially fixed distance from said radiation source throughout said scanning movement thereof.

13. An apparatus as recited in claims 1 , wherein said radiation detection means comprises an array of detector elements and said ultrasound transducer comprises an array of transducer elements, and wherein said arrays are oriented in like relation relative to said first path and second path, respectively.

14. An apparatus as recited in claims 1 , wherein at least one said radiation detection means and said ultrasound transducer is of a width that is less than a width of a selected region of a patient's body to be imaged.

15. An apparatus as recited in claims 1 , wherein said radiation detection means and said ultrasound transducer have corresponding widths which are each less than a width of a selected region of a patient's body to be imaged.

16. An apparatus as recited in claims 15 , wherein said radiation detection means and said ultrasound transducer have corresponding lengths which are each at least as great as a length of a selected region of a patient's body to be imaged.

17. An apparatus as recited in claim 1 , further comprising:

a display for displaying a plurality of images of said selected body region generated using said first and second image signals; and,

a user input for selecting a desired image by identifying a location of interest in a different image.

18. An apparatus as recited in claim 1 , wherein a pair of ultrasound transducers are positionable for scanning movement along substantially parallel paths, wherein one of said pair is located on a first side of said selected body region and the other of said pair is located on an opposing second side of said selected body region.

19. A method for use in obtaining image data for a selected region of a patient's body, comprising:

transmitting a radiation signal from a radiation source through a selected region of a patient's body;

moving a radiation detection means along a first path during said transmitting step, wherein said radiation detection means receives a portion of said radiation signal passing through a selected region of a patient's body and provides a first image signal responsive thereto; and,

displacing an ultrasound transducer along a second path that is one of the same and substantially coincidental to said first path, wherein said ultrasound transducer receives an ultrasound signal from said selected region of a patient's body and provides a second image signal responsive thereto.

20. A method as recited in claim 19 , further comprising:

immobilizing said selected region of a patient's body within a predetermined frame of reference, wherein said transmitting, moving and displacing steps are completed during said immobilizing step.

21. A method as recited in claim 20 , wherein said mobilizing step includes:

compressing said selected region of a patient's body.

22. A method as recited in claim 19 , wherein said radiation source is located on a first side of said selected body region and said radiation detection means and said ultrasound transducer are both positioned on an opposing second side thereof.

23. A method as recited in claim 19 , wherein said moving and displacing steps at least partially overlap.

24. A method as recited in claim 23 , wherein said moving and displacing steps are completed in substantial synchronicity.

25. A method as recited in claim 19 , wherein said moving and displacing steps are completed sequentially.

26. A method as recited in claim 19 , wherein said ultrasound transducer transmits said ultrasound signal into said selected body region during said displacing step.

27. A method as recited in claim 19 , wherein said displacing step includes:

displacing a pair of ultrasound transducers along substantially parallel paths, wherein one of said pair is located on a first side of said selected body region and the other of said pair is located on an opposing second side of said selected body region, and wherein said pair provide second image signals.

28. A method as recited in claim 19 , further comprising:

selecting a desired image for display by identifying a location of interest in a different displayed image.

Assignments (12)
RELEASE OF SECURITY INTEREST Recorded Apr 28, 2026
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: HOLOGIC, INC., ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO DIRECT RADIOGRAPHY CORP.; CYTYC CORPORATION, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO BIOLUCENT, LLC; CYTYC SURGICAL PRODUCTS, LLC, AS SUCCESSOR-BY-CONVERSION TO CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; GEN-PROBE INCORPORATED, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.
Reel/Frame 075566/0039 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 035820 FRAME: 0239. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY INTEREST RELEASE. Recorded Nov 9, 2017
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 044727/0529 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 028810 FRAME: 0745. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY AGREEMENT. Recorded Nov 9, 2017
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 044432/0565 →
SECURITY AGREEMENT Recorded Aug 7, 2015
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; DIRECT RADIOGRAPHY CORP.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 036307/0199 →
SECURITY INTEREST RELEASE REEL/FRAME 028810/0745 Recorded Jun 4, 2015
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 035820/0239 →
SECURITY AGREEMENT Recorded Aug 1, 2012
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 028810/0745 →
TERMINATION OF PATENT SECURITY AGREEMENTS AND RELEASE OF SECURITY INTERESTS Recorded Aug 25, 2010
From: GOLDMAN SACHS CREDIT PARTNERS, L.P., AS COLLATERAL AGENT
To: HOLOGIC, INC.; R2 TECHNOLOGY, INC.; SUROS SURGICAL SYSTEMS, INC.; BIOLUCENT, LLC; DIRECT RADIOGRAPHY CORP.; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS LIMITED PARTNERSHIP; CYTYC SURGICAL PRODUCTS II LIMITED PARTNERSHIP; CYTYC SURGICAL PRODUCTS III, INC.; CYTYC PRENATAL PRODUCTS CORP.; THIRD WAVE TECHNOLOGIES, INC.
Reel/Frame 024944/0315 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 17, 2010
From: FISCHER IMAGING CORPORATION
To: HOLOGIC, INC.
Reel/Frame 024838/0542 →
PATENT SECURITY AGREEMENT Recorded Jul 29, 2008
From: HOLOGIC, INC.
To: GOLDMAN SACHS CREDIT PARTNERS L.P., AS COLLATERAL AGENT
Reel/Frame 021301/0796 →
PATENT SECURITY AGREEMENT Recorded Oct 26, 2007
From: HOLOGIC, INC.
To: GOLDMAN SACHS CREDIT PARTNERS L.P.
Reel/Frame 020018/0818 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 15, 2007
From: FISCHER IMAGING CORPORATION
To: HOLOGIC, INC.
Reel/Frame 019440/0759 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 6, 2003
From: BESSON, GUY M.; NIELDS, MORGAN W.
To: FISCHER IMAGING CORPORATION
Reel/Frame 014157/0890 →