IP Library › Granted Patent US 7,166,576
Granted Patent B2
US 7,166,576 · App. 10/456,981 · Granted Jan 23, 2007

Methods for preserving organs and tissues

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Quick Facts
Patent No.
US 7,166,576
App. No.
10/456,981
Granted
Jan 23, 2007
Kind
B2
Abstract

The invention relates to a method for preserving an organ or tissue comprising contacting the organ or tissue with an effective amount of a kallikrein inhibitor and solutions useful for such a method. Also provided is a method for reducing reperfusion injury of an organ during surgery and/or following removal of the organ from a subject comprising placing the organ in an organ storage and preservative solution, wherein the solution comprises a kallikrein inhibitor.

Claims (3)

1. A composition for preserving and/or storing an organ comprising a physiologically acceptable ex vivo organ preservation solution containing a polypeptide comprising the amino acid sequence of SEQ ID NO:2 or amino acids 3–60 of SEQ ID NO:2.

2. The composition according to claim 1 , wherein the polypeptide comprises SEQ ID NO:2.

3. The composition of claim 1 , wherein the polypeptide comprises amino acids 3–60 of SEQ ID NO:2.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 18, 2021
From: DYAX CORP.
To: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Reel/Frame 056268/0983 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 17, 2003
From: CICARDI, MARCO; BERGAMASCHINI, LUIGI
To: DYAX CORP.
Reel/Frame 014596/0785 →