Orifice device for delivering drugs at low fluid flow rates
View Patent ↗An orifice device for delivering a drug includes an inner member having a proximal end and a distal end. A winding is helically wound around the inner member. The winding and the inner member define a first channel for carrying a drug therethrough. An inlet is at the proximal end of the winding and an outlet is at the distal end of the winding.
1. An orifice device for delivering a drug comprising:
an inner member having a proximal end and a distal end;
a winding helically wound around the inner member, wherein the winding comprises a wire and wherein the wire has a width ranging from 0.001-0.050 inches;
the exterior surface of the winding and the inner member defining a first channel having a helical flowpath following the curvature of the winding for carrying a drug therethrough and an inlet at the proximal end of the winding and an outlet at the distal end of the winding;
a first drug carrying path defined by a first inlet at the proximal end of the winding, the first channel having a helical flowpath following the curvature of the winding, and a first outlet at the distal end of the winding;
an outer member over the winding, wherein the exterior surface of the winding and the outer member define a second channel having a helical flow path following the curvature of the winding for carrying a drug therethrough; and
a second drug carrying path defined by a second inlet at the proximal end of the winding, the second channel having a helical flowpath following the curvature of the winding, and a second outlet at the distal end of the winding, wherein the first and second drug carrying paths are capable of delivering two separate drugs.
2. The orifice device according to claim 1 , wherein the wire has a circular shape in cross-section.
3. The orifice device according to claim 1 , wherein the wire has a hexagonal shape in cross-section.
4. The orifice device according to claim 1 , wherein the wire has an octagonal shape in cross-section.
5. The orifice device according to claim 1 , wherein the wire has a triangular shape in cross-section.
6. The orifice device according to claim 1 , wherein the outer member is a sleeve.
7. The orifice device according to claim 1 , wherein the outer member is made of a polymer material.
8. The orifice device according to claim 7 , wherein the polymer material is PTFE.
9. The orifice device according to claim 1 , wherein the wire is made of a degradation-resistant material.
10. The orifice device according to claim 9 , wherein the material is a nickel titanium alloy.
11. The orifice device according to claim 9 , wherein the material is a stainless steel alloy.
12. The orifice device according to claim 9 , wherein the material is plastic.
13. The orifice device according to claim 1 , wherein the wire has a width ranging from 0.004-0.005 inches.
14. An implantable drug delivery device comprising:
an inner member having a proximal end and a distal end;
a winding helically wound around the inner member, wherein the winding comprises a wire and wherein the wire has a width ranging from 0.001-0.050 inches;
the exterior surface of the winding and the inner member defining a first channel having a helical flowpath following the curvature of the winding for carrying a drug therethrough and an inlet at the proximal end of the winding and an outlet at the distal end of the winding;
a first drug carrying path defined by a first inlet at the proximal end of the winding, the first channel having a helical flowpath following the curvature of the winding, and a first outlet at the distal end of the winding;
an outer member over the winding, wherein the exterior surface of the winding and the outer member define a second channel having a helical flow path following the curvature of the winding for carrying a drug therethrough;
a second drug carrying path defined by a second inlet at the proximal end of the winding, the second channel having a helical flowpath following the curvature of the winding, and a second outlet at the distal end of the winding, wherein the first and second drug carrying paths are capable of delivering two separate drugs; and
a housing.
15. The implantable drug delivery device of claim 14 further comprising a pump device.
16. The implantable drug delivery device of claim 15 wherein the pump device is an osmotically driven ruminal bolus.
17. The implantable drug delivery device of claim 14 wherein the implantable drug delivery device is permanently implanted.
18. The implantable drug delivery device of claim 14 wherein the implantable drug delivery device is made of a biocompatible and bio absorbable material.