Method for manufacturing an orifice mechanism capable of low fluid flow rates
View Patent ↗A method for manufacturing an orifice mechanism includes the steps of providing a mandrel having a length and helically wrapping a winding around at least a portion of the length of the mandrel. The mandrel and the winding define a first channel for carrying a drug therethrough. An inlet is at one end of the winding and an outlet is at the other end of the winding.
1. A method of making a drug delivery device having a customized orifice mechanism, the method comprising the steps of:
providing a mandrel having a length;
selecting a winding comprising a desired wire type and a desired length;
helically wrapping the winding around at least a portion of the length of the mandrel; and
the mandrel and the winding defining a first channel for carrying a drug therethrough and an inlet at one end of the winding and an outlet at another end of the winding.
2. The method according to claim 1 , further comprising using a wire for the winding.
3. The method according to claim 2 , further comprising providing an outer member over the winding.
4. The method according to claim 3 , further comprising using the winding and the outer member to define a second channel for also carrying a drug therethrough.
5. The method according to claim 4 , further comprising using an outer member comprising a channel filling material for blocking drug flow through the second channel.
6. The method according to claim 2 , further comprising using a wire having a circular shape in cross-section.
7. The method according to claim 4 , further comprising using a wire having a circular shape in cross-section.
8. The method according to claim 2 , further comprising using a wire having a hexagonal shape in cross-section.
9. The method according to claim 4 , further comprising using a wire having a hexagonal shape in cross-section.
10. The method according to claim 2 , further comprising using a wire having an octagonal shape in cross-section.
11. The method according to claim 4 , further comprising using a wire having an octagonal shape in cross-section.
12. The method according to claim 2 , further comprising using a wire having a triangular shape in cross-section.
13. The method according to claim 3 , further comprising using a sleeve as an outer member.
14. The method according to claim 3 , further comprising using an outer member comprising a polymer material.
15. The method according to claim 14 , further comprising using a polymer material comprising PTFE.
16. The method according to claim 5 , further comprising using a glue as a channel filling material.
17. The method according to claim 2 , further comprising using a wire comprising made of a degradation-resistant material.
18. The method according to claim 17 , further comprising using a material is a nickel titanium alloy.
19. The method according to claim 17 , further comprising using a material comprising is a stainless steel alloy.
20. The method according to claim 17 , further comprising using a material comprising plastic.
21. The method according to claim 2 , further comprising using a wire having a width ranging from 0.001–0.050 inches.
22. The method according to claim 21 , further comprising using a wire having a width ranging from 0.004–0.005 inches.