Compositions comprising an o/w emulsion containing conjugated linoleic acid

1. A method of treatment of a human or non-human animal subject with a fungal infection by the parenteral administration of a lipophilic pharmaceutical agent comprising administering a composition comprising a lipophilic pharmaceutical agent in an oil-in-water emulsion containing a conjugated linoleic acid (CLA), wherein said conjugated linoleic acid forms at least 50% by weight of the oil in the emulsion, wherein said lipophilic pharmaceutical agent is griseofulvin.

2. The method as claimed in claim 1 , wherein said CLA is a single compound.

3. The method as claimed in claim 1 , wherein said CLA is a mixture of two or more CLA isomers.

4. The method as claimed in claim 1 , wherein said CLA is the cis-9, trans-11 isomer and/or the trans-10, cis-12 isomer.

5. The method as claimed in claim 4 , wherein said isomers are at least 80% wt cis-9, trans-11 and/or trans-10, cis-12.

6. The method as claimed in claim 5 , wherein said cis-9, trans-11 and trans-10, cis-12 isomers are in a weight ratio of from 2:98 to 98:2.

7. The method as claimed in claim 1 , wherein said CLA forms at least 90% wt of the oil phase in said emulsion.

8. The method as claimed in claim 1 , wherein said CLA is provided as a salt, ester or amide thereof.

9. The method as claimed in claim 1 , wherein oil droplets in said oil-in-water emulsions have mode droplet diameters in the range 160 to 6000 nm.

10. The method as claimed in claim 1 , wherein said emulsion contains 5 to 300 mg/mL of CLA or CLA derivative.

11. The method as claimed in claim 10 , wherein said emulsion contains 100 to 200 mg/mL of CLA or CLA derivative.

12. The method as claimed in claim 1 , wherein said emulsion has a viscosity at 20° C. of 100 mPas or less.