Genes with ES cell-specific expression
View Patent ↗The present invention relates to a probe for selecting ES cells, which characteristically contains one of DNAs having base sequences depicted in SEQ ID Nos; 1, 2, 3, 4, 5, 6, 7 and 8, or DNAs having base sequences depicted in SEQ ID Nos; 9, 11, 13, 15, 17, 19, 21, 23 and 41 and a screening method of ES cell using this probe. Preparation of a probe for selecting ES cells becomes feasible by identifying plural gene with ES cell-specific expressions (ECAT genes) and using the information of the base sequences of these gene groups. Efficient selection of ES cell enables supply of a large amount of ES cell expected to be applicable to regenerative medicine.
1. An isolated nucleic acid comprising a DNA comprising SEQ ID NO: 15.
2. A vector comprising the nucleic acid of claim 1 .
3. An isolated cell comprising the vector of claim 2 .
4. An isolated probe for selecting mouse ES cells, wherein the probe comprises the nucleic acid of claim 1 .