Medicinal use of histone deacetylase inhibitor and method of evaluating antitumor effect thereof
View Patent ↗A therapeutic agent for prostate cancer and malignant lymphoma containing FK228 or a salt thereof as an active ingredient, and a method for evaluating an antitumor effect of a histone deacetylase inhibitor which includes at least a step of treating a test cell with a histone deacetylase inhibitor, a step of measuring change in the expression amount of a specific gene in the test cell before and, after the treatment with the inhibitor, comparing the both expression amounts.
1. A method for treating prostate cancer, which comprises administering an effective amount of a compound represented by the formula (I)
or a salt thereof to a patient in need thereof.
2. The method of claim 1 , wherein the compound represented by the formula (I) is a compound represented by the formula (II)