Method for aiding implantation or decreasing miscarriage rate
View Patent ↗The invention provides a protocol leading to improved embryo implantation rates and/or decreased miscarriage rates in which hCG or LH, or a bio-analogue thereof, is administered during the follicular phase.
1. A method for aiding/encouraging implantation and/or decreasing miscarriage rates of an embryo in a human patient, comprising administering human luteinising hormone (hLH) during controlled ovarian hyperstimulation (COH) in a human patient in need thereof, while continuing administration of FSH, wherein the hLH is administered starting between the 3 rd and 10 th day after commencing treatment with FSH, to aid/encourage implantation and/or decrease miscarriage rates of an embryo in the human patient.
2. The method according to claim 1 , wherein the hLH is administered at a dosage of 125-7000 IU hLH/day.
3. The method according to claim 1 , wherein the hLH is administered starting between the 3 rd and 8 th day after commencing treatment with FSH.
4. The method according to claim 3 , wherein the human patient is at least 35 years of age.
5. The method according to claim 1 , wherein the hLH is recombinant hLH.
6. The method according to claim 1 , wherein the hLH is urinary hLH.