IP Library › Patent Application 10494964
Patent Application
App. No. 10/494,964

Antibody stimulating il-ira production

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Quick Facts
Patent No.
US None
App. No.
10/494,964
Abstract

The invention concerns natural antibodies eventually monoclonal capable of inducing a high production of IL-1Ra with monocytes or macrophages and the use of said antibodies for treating inflammatory or autoimmune diseases.

Claims (3)

1 . A monoclonal IgG class antibody which reacts with the hapten DNP and at least one autoantigen selected from myosin, actin, myelin basic protein (MBP) and tubulin, characterized in that it induces over-expression of IL-1Ra in macrophages or monocytes.

2 . The antibody as claimed in claim 1 , characterized in that it does not react with tetanus toxoid.

3 - 23 . (canceled)

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 11, 2009
From: LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES
To: LFB BIOTECHNOLOGIES
Reel/Frame 022378/0106 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 27, 2005
From: BOUREL, DOMINIQUE; BRULEY-ROSSET, MARTINE; DHAINAUT, FREDERIC; LIROCHON, JACKY
To: LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES
Reel/Frame 016173/0215 →