Intervertebral disk prosthesis or nucleus replacement prosthesis
An intervertebral disk prosthesis or nucleus replacement prosthesis includes a bio-compatible pouch ( 1 ) receiving a curable, flowable material ( 2 ). The curable flowable material includes monomers, comonomers, homopolymers, oligomers or mixtures thereof. Curing the curable, flowable material introduced into the pouch ( 1 ) takes place in situ after the prosthesis is installed in the intervertebral space between two adjacent vertebras.
1 . An intervertebral disk prosthesis or nucleus replacement prosthesis comprising a bio-compatible pouch ( 1 ) receiving a curable, flowable material ( 2 ), said curable, flowable material including a material selected from the group consisting of monomers, comonomers, homopolymers, oligomers, and mixtures thereof,
wherein at walls ( 6 , 7 ) designed to rest against upper plates ( 13 , 14 ) of adjacent vertebras ( 11 , 12 ), the pouch ( 1 ) is thicker than in remaining wall segments that are not designed to rest against the upper plates of adjacent vertebras.
2 . The intervertebral disk prosthesis as claimed in claim 1 , wherein the flowable material ( 2 ) contains a photo-initiator.
3 . The intervertebral disk prosthesis as claimed in claim 2 , wherein the photo-initiator absorbs light in the 340 to 420 nm range.
4 . The intervertebral disk prosthesis as claimed in claim 2 , wherein the photo-initiator is a selected from the group consisting of phosphine oxide and acylphosphine oxide.
5 . The intervertebral disk prosthesis as claimed in claim 4 , wherein the phosphine oxide is copolymerized with dimethylacryl amide.
6 . The intervertebral disk prosthesis as claimed in claim 1 , wherein the monomers, comonomers, homopolymers, oligomers or mixtures thereof are selected from the group of
(a) polyethylene glycols, including polyethyleneglycol (di)acrylates;
(b) N-vinylpyrrolidones; and
(c) vinyls, including vinyl alcohols; and
(d) styrenes.
7 . The intervertebral disk prosthesis as claimed in claim 1 , wherein a weight percent of water of the flowable material ( 2 ) is selected from the group of ranges consisting of 30 to 160% water and 40 to 90% water.
8 . The intervertebral disk prosthesis as claimed in claim 1 , wherein the flowable material ( 2 ) contains a hydrogel.
9 . The intervertebral disk prosthesis as claimed in claim 1 , wherein the pouch ( 1 ) has a double-walled structure and the flowable material ( 2 ) is introduced between two walls ( 3 , 4 ) of the double-walled structure whereby a center ( 5 ) of the intervertebral disk prosthesis is hollow.
10 . The intervertebral disk prosthesis as claimed in claim 1 , wherein the pouch ( 1 ) is made of a memory-effect substance whereby said pouch shall assume a previously stored geometric shape at body temperature.
11 . The intervertebral disk prosthesis as claimed in claim 1 , wherein the flowable material ( 2 ) further includes a material selected from the group consisting of a polymerization catalyst and a polymerization accelerator.
12 . The intervertebral disk prosthesis as claimed in claim 1 , wherein the pouch ( 1 ) is made of a substance that is chemically identical to the material contained in the pouch.
13 . The intervertebral disk prosthesis as claimed in claim 1 , wherein, at its walls ( 6 , 7 ) touching the upper plates ( 13 , 14 ) of the adjacent vertebras ( 11 , 12 ), the pouch ( 1 ) is made relatively thicker and preferably consists of a material selected from the group consisting of polycarbonate urethane (PCU) and polycarbonate.
14 . A method for manufacturing an intervertebral disk prosthesis or a nucleus replacement prosthesis, comprising the steps of:
(a) implanting a bio-compatible pouch ( 1 ) in the intervertebral space ( 10 ) of two adjacent vertebras ( 11 , 12 ),
(b) introducing a curable, flowable material ( 2 ) inside the implanted, biocompatible pouch ( 1 ), said flowable material including materials selected from the group consisting of monomers, comonomers, oligomers and mixtures thereof, the pouch ( 1 ) when filled remaining centered in the intervertebral space ( 10 ); and,
(c) curing in situ the curable, flowable material ( 2 ) that is disposed within the pouch ( 1 ).
15 . The method as claimed in claim 14 , wherein the material ( 2 ) is cured by photo-polymerization using visible or ultraviolet light.
16 . The method as claimed in claim 14 , wherein the pouch ( 1 ) is inflated with air between the steps (a) and (b).
17 . The method as claimed in claim 14 , wherein, between the steps (a) and (b), the pouch ( 1 ) is filled with an x-ray contrast means.
18 . The method as claimed in claim 14 , wherein the flowable material ( 2 ) is cured by auto-polymerization.
19 . The method as claimed in claim 14 , wherein the material ( 2 ) is introduced substantially at no excess pressure into the pouch ( 1 ).
20 . The method as claimed in claim 14 , wherein the material ( 2 ) is introduced into the pouch ( 1 ) at an excess pressure, said excess pressure being selected from the group of ranges consisting of less than 3 atm and less than 1.1 atm.
21 . (canceled)