IP Library › Granted Patent US 7,259,291
Granted Patent B2
US 7,259,291 · App. 10/498,286 · Granted Aug 21, 2007

Enucleation of avian eggs by gamma irradiation

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Quick Facts
Patent No.
US 7,259,291
App. No.
10/498,286
Granted
Aug 21, 2007
Kind
B2
Abstract

A method of enucleating an egg by exposing the egg to gamma irradiation. The dose of gamma irradiation used is sufficiently high to halt development of the egg or embryo derived therefrom directed by the nucleus of the irradiated egg, but sufficiently low to enable development of the egg or embryo directed by a nucleus transferred into the enucleated egg.

Claims (7)

1. A method of enucleating an avian egg, wherein the egg is exposed to gamma radiation, wherein the dose of gamma radiation is sufficiently high to halt development of the egg or an embryo derived therefrom directed by the nucleus of the irradiated egg, but sufficiently low to enable development of the egg or embryo directed by a nucleus transferred into the enucleated egg, wherein the total dose of gamma irradiation is greater than 7 Gy.

2. The method according to claim 1 , wherein the egg is exposed to gamma radiation for a period of time between 1 and 3 minutes.

3. The method according to claim 1 , wherein the total dose of gamma radiation is greater than 10 Gy.

4. The method according to claim 1 , wherein the total dose of gamma radiation is greater than 12 Gy.

5. The method according to claim 1 , wherein the total dose of gamma radiation is in the range of 12 Gy to 14 Gy.

6. The method according to claim 1 , wherein the wherein the total dose of gamma radiation is in the range 37 Gy to 62.5 Gy.

7. The method according to claim 1 , wherein the total dose of gamma radiation is in the range 44.5 Gy to 47.5 Gy.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 25, 2016
From: GALAXY MERGER SUB LLC
To: ALEXION PHARMA LLC
Reel/Frame 037574/0299 →
CHANGE OF NAME Recorded Jan 30, 2009
From: AVIGENICS, INC.
To: SYNAGEVA BIOPHARMA CORP.
Reel/Frame 022177/0940 →
PURCHASE OF INTELLECTUAL PROPERTY ASSETS Recorded Oct 2, 2008
From: SONEET KAPILA, IN HIS CAPACITY AS ASSIGNEE FOR THE BENEFIT OF CREDITORS OF VIRAGEN, INC., A DELAWARE CORPORATION, AND ASSIGNEE FOR THE BENEFIT OF CREDITORS OF VIRAGEN INTERNATIONAL, INC., A DELAWARE CORPORATION
To: AVIGENICS, INC.
Reel/Frame 021630/0191 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 4, 2004
From: SANG, HELEN; SHERMAN, ADRIAN
To: VIRAGEN INCORPORATED
Reel/Frame 015824/0789 →