IP Library › Granted Patent US 8,673,888
Granted Patent B2
US 8,673,888 · App. 10/508,958 · Granted Mar 18, 2014

Depsipeptide for therapy of kidney cancer

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Quick Facts
Patent No.
US 8,673,888
App. No.
10/508,958
Granted
Mar 18, 2014
Kind
B2
Abstract

The present invention provides a therapeutic agent of kidney cancer, which comprises FK228 of the formula (I) or a salt thereof. FK228 or a salt thereof, which is an active ingredient in the present invention, shows a superior antitumor activity in vivo against kidney cancer.

Claims (8)

1. A method of treating kidney cancer in a mammal in need thereof, which comprises administering an effective amount of a compound of the formula (I)

or a salt thereof to said mammal.

2. The treatment method of kidney cancer according to claim 1 , wherein the compound of the formula (I) is a compound of the formula (II)

3. The treatment method of kidney cancer according to claim 1 , wherein the mammal is a human.

4. A method of suppressing growth of a cancerous tumor of the kidney in vivo in a mammal in need thereof, which comprises administering an effective amount of a compound of the formula (I)

or a salt thereof to said mammal.

5. The method of suppressing growth of the cancerous tumor of the kidney according to claim 4 , wherein the compound of the formula (I) is a compound of the formula (II)

6. The method of claim 4 , wherein the in vivo means in a body of a human.

Assignments (2)
MERGER Recorded Dec 12, 2005
From: FUJISAWA PHARMACEUTICAL CO., LTD.
To: ASTELLAS PHARMA INC.
Reel/Frame 017073/0257 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 7, 2005
From: NAOE, YOSHINORI; BATES, SUSAN E.
To: FUJISAWA PHARMACEUTICAL CO., LTD.; HEALTH AND HUMAN SERVICES, THE GOVERNMENT OF THE UNITED STATES, REPRESENTED BY THE SECRETARY, DEPARTMENT OF
Reel/Frame 016758/0674 →