Association of an antithrombotic and aspirin
View Patent ↗The present invention relates to a new combination of an antithrombotic and aspirin and to pharmaceutical compositions comprising them.
1. A composition comprising a combination of compound (A) of formula (I), optionally in the form of an optical isomer, or a pharmaceutically acceptable salt thereof, and aspirin, or a pharmaceutically acceptable salt thereof:
wherein compound (A) of formula (I), or an optical isomer or pharmaceutically acceptable salt thereof, is present in a range of from 1 to 300 mg, and aspirin, or a pharmaceutically acceptable salt thereof is present in a range of from 100 to 300 mg.
2. The composition of claim 1 , wherein compound (A) has the (R) configuration.
3. The composition of claim 1 , wherein compound (A) is in the form of a sodium salt.
4. A pharmaceutical composition comprising as active ingredients a combination of compound (A), optionally in the form of an optical isomer, or a pharmaceutically acceptable salt thereof, and aspirin, or a pharmaceutically acceptable salt thereof, wherein compound (A), or an optical isomer or pharmaceutically acceptable salt thereof, is present in a range of from 1 to 300 mg, and aspirin, or a pharmaceutically acceptable salt thereof is present in a range of from 100 to 300 mg, in combination with one or more pharmaceutically acceptable, inert excipients or carriers.
5. The pharmaceutical composition of claim 4 , wherein compound (A) has the (R) configuration.
6. The pharmaceutical composition of claim 4 , wherein compound (A) is in the form of a sodium salt.