Microcrystalline cellulose compositions
View Patent ↗Ultra-fine microcrystalline cellulose compositions are disclosed which comprise co-attrited microcrystalline cellulose and a hydrocolloid. The compositions have a mean particle size of less thin 10 microns. The compositions are prepared by subjecting a high solids mixture of microcrystalline cellulose and a hydrocolloid to high shear forces in the presence of an anti slip agent preferably an aqueoussolution of an inorganic salt. The compositions are especially useful in food pharmaceutical and cosmetic and industrial applications.
1. A composition comprising
(a) at least 70% by weight microcrystalline cellulose,
(b) a hydrocolloid, and
(c) a water soluble anti-slip agent in an amount of from about 0.8% to about 3.0% by weight based on the total weight of solids in said composition, wherein the composition has a mean particle size of less than about 10 microns.
2. The composition as claimed in claim 1 , wherein
(i) when the hydrocolloid is a carrageenan at least about 50% of the particles have a particle size less than about 3.5 microns,
(ii) when the hydrocolloid is a hydrocolloid other than a carrageenan at least about 30% of the particles have a particle size less than about 3.5 microns, and
(iii) when the hydrocolloid is a combination of a carrageenan and another hydrocolloid at least about 20% of the particles have a particle size less than about 3.5 microns.
3. The composition as claimed in claim 1 having a Ca++ content of from 0.18 to 3.5% by weight based on the total weight of the composition.
4. The composition as claimed in claim 1 wherein the amount of hydrocolloid is equal to from 15% to 30% by weight based on the total weight of hydrocolloid and microcrystalline cellulose.
5. The composition as claimed in claim 1 wherein the hydrocolloid is a carrageenan.
6. The composition as claimed in claim 1 wherein the hydrocolloid is an alginate.
7. The composition as claimed in claim 1 wherein the amount of microcrystalline cellulose is equal to from 70% to 85% by weight based on the total weight of hydrocolloid and microcrystalline cellulose.
8. The composition as claimed in claim 1 wherein said water soluble anti-slip agent comprises an inorganic salt.
9. The composition as claimed in claim 8 wherein the inorganic salt is selected from the group consisting of sodium chloride, calcium chloride, calcium lactate, calcium tartrate, and calcium monophosphate.
10. The composition as claimed in claim 8 wherein the inorganic salt is calcium chloride.
11. The composition as claimed in claim 1 , wherein the microcrystalline cellulose and the hydrocolloid are coattrited.
12. A food product comprising the composition of claim 1 .
13. A pharmaceutical composition comprising the composition of claim 1 .
14. A cosmetic composition comprising the composition of claim 1 .
15. A pharmaceutical dosage form comprising the composition of claim 1 .
16. An industrial composition comprising the composition of claim 1 .
17. The composition according to claim 1 wherein a 2.6% dispersion of the composition in water at room temperature has a viscosity of at least about 1000 centipoise.
18. The composition according to claim 1 wherein a 2.6% dispersion of the composition in water at room temperature has a viscosity of at least about 5000 centipoise.
19. The composition according to claim 1 wherein a 2.6% dispersion of the composition in water at room temperature has a viscosity of at least about 10,000 centipoise.
20. A process for preparing a microcrystalline cellulose composition, said process comprising:
(a) forming a mixture of microcrystalline cellulose, a hydrocolloid, and a water soluble anti-slip agent and
(b) kneading the mixture,
wherein the amount of the anti-slip agent in the mixture is from about 0.8% to about 3.0% by weight based on the total weight of solids in the mixture.
21. The process as claimed in claim 20 wherein the microcrystalline cellulose is combined with the hydrocolloid before the anti-slip agent is added.
22. The process as claimed in claim 20 wherein the microcrystalline cellulose is combined with the anti-slip agent before the hydrocolloid is added.
23. The process of claim 20 in which the hydrocolloid is selected from the group consisting of carrageenans and alginates.
24. The process of claim 20 in which the hydrocolloid is a carrageenan.
25. The process of claim 24 in which the anti-slip agent is an inorganic salt.
26. The process of claim 25 in which the amount of inorganic salt is equal to from 1.0% to 3.0% by weight based on the total weight of solids in the mixture.
27. The process of claim 20 in which the hydrocolloid is an alginate.
28. The process of claim 27 in which the anti-slip agent is an inorganic salt.
29. The process of claim 28 in which the amount of inorganic salt is equal to from 0.8% to 2.0% by weight based on the total weight of solids in the mixture.
30. The process of claim 20 in which the anti-slip agent is an aqueous solution of an inorganic salt.
31. The process of claim 30 in which the inorganic salt is a divalent salt.
32. The process of claim 31 in which the divalent salt is calcium chloride.
33. The process according to claim 20 wherein the microcrystalline cellulose used to form the mixture is microcrystalline cellulose wetcake having a solids content of from 38% to 44% by weight.