Remedy for pemphigoid
View Patent ↗An agent for treatment of pemphigoid is provided. For use as an agent for treatment of pemphigoid, IFN-γ is administered in a dose of 2,000,000 JRU once daily for 7 days by intravenous drip infusion. Depending on symptoms, side effects and age of a patient, the dose can be change, or the dosage can changed to intravenous drip infusion given once in several days. IFN-γ is fast-acting against pemphigoid, involves few side effects, and is considered to be effective. The mechanism of action is presumed to be that IFN-γ suppresses the chemotaxis and function of eosinophils which are considered to be directly involved in the occurrence of pemphigoid.
1. A method for treating bullous pemphigoid comprising administering to a human patient in need of such treatment human interferon-γ intravenously in a daily dose of 2,000,000-4,000,000 Japanese Reference Units (JRU).
2. The method according to claim 1 , wherein said daily dose is 2,000,000 JRU.
3. The method according to claim 1 , comprising administering human interferon-γ in combination with an antihistaminic, an antiallergic, a corticosteroid, or any combination thereof.
4. The method of claim 3 , comprising administering human interferon-γ in combination with an antihistaminic.
5. The method of claim 3 , comprising administering human interferon-γ in combination with an antiallergic.
6. The method of claim 3 , comprising administering human interferon-γ in combination with a corticosteroid.
7. The method of claim 1 , wherein said human interferon-γ is administered for seven consecutive days.