IP Library › Granted Patent US 7,538,257
Granted Patent B2
US 7,538,257 · App. 10/532,520 · Granted May 26, 2009

Fluid wound dressing comprising partially cured polyurethane

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Quick Facts
Patent No.
US 7,538,257
App. No.
10/532,520
Granted
May 26, 2009
Kind
B2
Abstract

A wound dressing composition comprising a partially cured polyurethane fluid. The composition can be injected directly into a wound, where it cures to form a wound filling dressing. Also provided is a wound dressing comprising such a composition. Also provided is a kit for the preparation of such wound dressings, the kit comprising (a) a polyurethane prepolymer; and (b) a curing agent for the polyurethane prepolymer. Preferably, the polyurethane components comprise reaction products of a diisocyanate with castor oil or a related ester of ricinoleic acid or its derivatives.

Claims (6)

1. A fluid wound dressing composition comprising a partially cured polyurethane fluid prepared by mixing: (a) a polyurethane prepolymer comprising an isocyanate capped prepolymer with (b) a curing agent for the polyurethane prepolymer, wherein said fluid wound dressing composition comprises from about 0.1 wt% to about 4 wt% of unreacted isocyanate.

2. A wound dressing composition according to claim 1 , wherein the composition comprises at least 50% by weight of polyurethane components.

3. A fluid wound dressing composition according to claim 1 , further comprising an additives selected from the group consisting of humectants, plasticizers, hydrocolloids, blowing agents, medicaments, and mixtures thereof.

4. A fluid wound dressing composition according to claim 1 , wherein the composition has a curing time at 25° C. of from about 0.1 to about 100 minutes.

5. A wound dressing according to claim 1 , further comprising reinforcing elements to assist removal of the cured polyurethane composition in one piece from a wound.

6. A wound dressing according to claim 1 , further comprising drainage elements to assist drainage of exudates from wounds.

Assignments (18)
RELEASE OF SECURITY INTEREST IN PATENTS Recorded Nov 7, 2019
From: WILMINGTON TRUST, NATIONAL ASSOCIATION
To: KCI USA, INC.; KCI LICENSING, INC.
Reel/Frame 050966/0547 →
RELEASE OF SECURITY INTEREST IN PATENTS Recorded Nov 6, 2019
From: WILMINGTON TRUST, NATIONAL ASSOCIATION
To: KINETIC CONCEPTS, INC.; KCI USA, INC.; ACELITY L.P. INC.; CHIRON HOLDINGS, INC.; CHIRON TOPCO, INC.; KCI ANIMAL HEALTH, LLC; KCI HOLDING COMPANY, INC.; KCI HOMECARE, INC.; KCI IMPORTS, INC.; KCI INTERNATIONAL, INC.; KCI LICENSING, INC.; KCI PROPERTIES LIMITED; KCI REAL HOLDINGS, L.L.C.; KCI REAL PROPERTY LIMITED; KCI USA REAL HOLDINGS, L.L.C.; TECHNIMOTION, LLC
Reel/Frame 050945/0278 →
RELEASE OF SECURITY INTEREST Recorded Oct 11, 2019
From: BANK OF AMERICA, N.A.
To: KCI USA, INC.
Reel/Frame 050710/0955 →
RELEASE OF SECURITY INTEREST REEL/FRAME 040098/0268 Recorded Feb 8, 2017
From: WILMINGTON TRUST
To: KCI USA, INC.
Reel/Frame 041666/0320 →
SECURITY AGREEMENT Recorded Feb 7, 2017
From: KCI USA, INC., AS GRANTOR
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 041650/0013 →
RELEASE OF SECURITY INTEREST IN INTELLECTUAL PROPERTY Recorded Feb 6, 2017
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: KCI LICENSING, INC., AS GRANTOR; TECHNIMOTION, LLC, A DELAWARE LIMITED LIABILITY COMPANY, AS GRANTOR; SYSTAGENIX WOUND MANAGEMENT (US), INC., A DELAWARE CORPORATION, AS GRANTOR
Reel/Frame 041395/0044 →
LIMITED THIRD LIEN INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Oct 7, 2016
From: KCI USA, INC.; LIFECELL CORPORATION; KCI LICENSING, INC.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 040291/0237 →
SECOND LIEN SECURITY AGREEMENT Recorded Sep 21, 2016
From: KCI USA, INC.; LIFECELL CORPORATION; KCI LICENSING, INC.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 040098/0268 →
SECURITY INTEREST Recorded Feb 17, 2016
From: KINETIC CONCEPTS, INC.; KCI USA, INC.; ACELITY L.P. INC.; CHIRON HOLDINGS, INC.; CHIRON TOPCO, INC.; KCI ANIMAL HEALTH, LLC; KCI HOLDING COMPANY, INC.; KCI HOMECARE, INC.; KCI IMPORTS, INC.; KCI INTERNATIONAL, INC.; KCI LICENSING, INC.; KCI PROPERTIES LIMITED; KCI REAL HOLDINGS, L.L.C.; KCI REAL PROPERTY LIMITED; KCI USA REAL HOLDINGS, L.L.C.; LIFECELL CORPORATION; TECHNIMOTION, LLC
To: WILMINGTON TRUST, NATIONAL ASSOCIATION
Reel/Frame 037845/0497 →
MERGER AND CHANGE OF NAME Recorded May 11, 2015
From: SYSTAGENIX WOUND MANAGEMENT (US),INC.; KCI USA, INC.
To: KCI USA, INC.
Reel/Frame 035645/0178 →
MERGER AND CHANGE OF NAME Recorded Feb 11, 2015
From: SYSTAGENIX WOUND MANAGEMENT (US), INC.; KCI USA, INC.
To: KCI USA, INC.
Reel/Frame 034954/0870 →
SECURITY AGREEMENT Recorded Oct 29, 2013
From: SYSTAGENIX WOUND MANAGEMENT (US), INC.
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 031508/0011 →
RELEASE OF SECURITY INTEREST Recorded Oct 28, 2013
From: J.P. MORGAN EUROPE LIMITED
To: SYSTAGENIX WOUND MANAGEMENT (US), INC.
Reel/Frame 031506/0186 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 21, 2010
From: ETHICON, INC.; JOHNSON & JOHNSON; JOHNSON & JOHNSON MEDICAL LIMITED; JOHNSON & JOHNSON MEDICAL B.V.; JANSSEN PHARMACEUTICA N.V.; CILAG AG; CILAG HOLDING AG; JEVCO LIMITED
To: SYSTAGENIX WOUND MANAGEMENT (US), INC.; SYSTAGENIX WOUND MANAGEMENT IP CO. B.V.
Reel/Frame 024563/0368 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 21, 2010
From: JOHNSON & JOHNSON MEDICAL LIMITED
To: SYSTAGENIX WOUND MANAGEMENT IP CO. B.V.
Reel/Frame 024563/0265 →
SECURITY AGREEMENT Recorded Jan 30, 2009
From: SYSTAGENIX WOUND MANAGEMENT (US), INC.
To: J.P. MORGAN EUROPE LIMITED
Reel/Frame 022177/0037 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 8, 2009
From: ETHICON, INC.; JOHNSON & JOHNSON MEDICAL LIMITED
To: SYSTAGENIX WOUND MANAGEMENT (US), INC.
Reel/Frame 022071/0762 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 25, 2006
From: ADDISON, DEBORAH; SCHONFELD, EDWARD; WACHTEL, PETER; STEPHENS, SALLY-ANNE
To: ETHICON, INC.
Reel/Frame 017211/0564 →