PERORAL PREPARATION FOR PREVENTION OR TREATMENT OF ATOPIC DERMATATIS
In accordance with the present invention, a peroral preparation, food and drink, feed, food additive or feed additive for prevention or treatment of atopic dermatitis comprising hydroxyproline or N-acylated derivative of hydroxyproline or a salt thereof is able to be provided and, particularly, said peroral preparation, food and drink, feed, food additive or feed additive comprising 0.1 to 90% by weight of hydroxyproline or N-acylated derivative of hydroxyproline or a salt thereof is able to be provided.
1 . A peroral preparation for prevention or treatment of atopic dermatitis comprising hydroxyproline or N-acylated derivative of hydroxyproline or a salt thereof.
2 . The peroral preparation according to claim 1 , wherein it comprises 0.1 to 90% by weight of hydroxyproline or N-acylated derivative of hydroxyproline or a salt thereof.
3 . The peroral preparation according to claim 1 or 2 , wherein the acyl group of N-acylated derivative of hydroxyproline is an acyl group having 1 to 24 carbon atoms.
4 . The peroral preparation according to claim 3 , wherein the N-acylated derivative of hydroxyproline is N-acetylated derivative, N-propionylated derivative, N-butyrylated derivative or isobutyrylated derivative.
5 . Food and drink or feed for prevention or treatment of atopic dermatitis comprising hydroxyproline or N-acylated derivative of hydroxyproline or a salt thereof.
6 . The food and drink or feed according to claim 5 , wherein it comprises 0.1 to 90% by weight of hydroxyproline or N-acylated derivative of hydroxyproline or a salt thereof.
7 . The food and drink or feed according to claim 5 or 6 , wherein the acyl group of N-acylated derivative of hydroxyproline is an acyl group having 1 to 24 carbon atoms.
8 . The food and drink or feed according to claim 7 , wherein the N-acylated derivative of hydroxyproline is N-acetylated derivative, N-propionylated derivative, N-butyrylated derivative or isobutyrylated derivative.
9 . Food additive or feed additive for prevention or treatment of atopic dermatitis comprising hydroxyproline or N-acylated derivative of hydroxyproline or a salt thereof.
10 . The food additive or feed additive according to claim 9 , wherein it comprises 0.1 to 90% by weight of hydroxyproline or N-acylated derivative of hydroxyproline or a salt thereof.
11 . The food additive or feed additive according to the claim 9 or 10 , wherein the acyl group of N-acylated derivative of hydroxyproline is an acyl group having 1 to 24 carbon atoms.
12 . The food additive or feed additive according to claim 11 , wherein the N-acylated derivative of hydroxyproline is N-acetylated derivative, N-propionylated derivative, N-butyrylated derivative or isobutyrylated derivative.
13 . A method of preventing or treating atopic dermatitis, which comprises orally administering or ingesting hydroxyproline or N-acylated derivative of hydroxyproline or a salt thereof in an effective amount.
14 . Use of hydroxyproline or N-acylated derivative of hydroxyproline or a salt thereof for the manufacture of peroral preparation, food, feed, food additive or feed additive for prevention or treatment of atopic dermatitis.