Hsp60 from arthrobacter
View Patent ↗The hsp60 gene from a strain of Arthrobacter has been isolated and sequenced. The encoded protein is believed to be highly immunogenic, especially in fish, and also has utility as a non-specific adjuvant, and as an adjuvanting carrier for heterologous antigens.
1. An isolated polynucleotide comprising a sequence selected from the group consisting of the sequence of SEQ ID NO:1, nucleotides 953-2578 of SEQ ID NO:1, and a sequence encoding the amino acid sequence of SEQ ID NO:2.
2. A plasmid comprising the polynucleotide of claim 1 .
3. An expression vector comprising the polynucleotide of claim 1 .
4. An immunogenic composition comprising the expression vector of claim 3 and a pharmaceutically acceptable carrier.
5. An isolated host cell comprising the expression vector of claim 3 .
6. An immunogenic composition comprising the host cell of claim 5 .